Evidence map›Paper›PMID 28018592›Full record

ArticleMultidisciplinary respiratory medicine2016

DNA damage and repair capacity in lymphocyte of chronic obstructive pulmonary diseases patients during physical exercise with oxygen supplementation.

Andréa Lúcia Gonçalves da Silva, Thaís Evelyn Karnopp, Augusto Ferreira Weber, Cassia da Luz Goulart, Paloma de Borba Scheneiders, Dannuey Machado Cardoso, Lisiane Lisboa Carvalho, Joel Henrique Ellwanger, Lia Gonçalves Possuelo, Andréia Rosane de Moura Valim

Open access · goldAbstract read
In one paragraph

Article in Multidisciplinary respiratory medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Andréa Lúcia Gonçalves da SilvaDepartamento de Educação Física e Saúde, Universidade de Santa Cruz do Sul - UNISC, Avenida Independência, 2293, Bairro Universitário, Santa Cruz do Sul, RS CEP 96815-900 Brazil ; Hospital Santa Cruz, Santa Cruz do Sul, RS Brazil.ORCID 0000-0001-8731-689X
Thaís Evelyn KarnoppDepartamento de Biologia e Farmácia, Universidade de Santa Cruz do Sul - UNISC, Santa Cruz do Sul, RS Brazil.
Augusto Ferreira WeberDepartamento de Biologia e Farmácia, Universidade de Santa Cruz do Sul - UNISC, Santa Cruz do Sul, RS Brazil.
Cassia da Luz GoulartDepartamento de Educação Física e Saúde, Universidade de Santa Cruz do Sul - UNISC, Avenida Independência, 2293, Bairro Universitário, Santa Cruz do Sul, RS CEP 96815-900 Brazil.
Paloma de Borba ScheneidersDepartamento de Educação Física e Saúde, Universidade de Santa Cruz do Sul - UNISC, Avenida Independência, 2293, Bairro Universitário, Santa Cruz do Sul, RS CEP 96815-900 Brazil.
Dannuey Machado CardosoDepartamento de Educação Física e Saúde, Universidade de Santa Cruz do Sul - UNISC, Avenida Independência, 2293, Bairro Universitário, Santa Cruz do Sul, RS CEP 96815-900 Brazil.
Lisiane Lisboa CarvalhoDepartamento de Educação Física e Saúde, Universidade de Santa Cruz do Sul - UNISC, Avenida Independência, 2293, Bairro Universitário, Santa Cruz do Sul, RS CEP 96815-900 Brazil ; Hospital Santa Cruz, Santa Cruz do Sul, RS Brazil.
Joel Henrique EllwangerPrograma de Pós-Graduação em Genética e Biologia Molecular, Departamento de Genética, Universidade Federal do Rio Grande do Sul - UFRGS, Porto Alegre, RS Brazil.
Lia Gonçalves PossueloDepartamento de Biologia e Farmácia, Universidade de Santa Cruz do Sul - UNISC, Santa Cruz do Sul, RS Brazil ; Programa de Pós-Graduação em Promoção da Saúde, Universidade de Santa Cruz do Sul - UNISC, Santa Cruz do Sul, RS Brazil.
Andréia Rosane de Moura ValimDepartamento de Biologia e Farmácia, Universidade de Santa Cruz do Sul - UNISC, Santa Cruz do Sul, RS Brazil ; Programa de Pós-Graduação em Promoção da Saúde, Universidade de Santa Cruz do Sul - UNISC, Santa Cruz do Sul, RS Brazil.
Universidade de Santa Cruz do Sul · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe hypothesized that the use of oxygen supplementation during aerobic exercise induces less DNA damage than exercise alone. The aim of this study is to assess the level of DNA damage induced by physical exercise with and without oxygen supplementation in chronic obstructive pulmonary diseases (COPD) patients.

methodsPeripheral blood was collected before and after aerobic exercise in two conditions: (I) aerobic exercise without oxygen supplementation (AE group) and (II) with oxygen supplementation (AE-O

resultsAE group showed lower induced damage (1 h of MMS treatment) and consequently less DNA repair compared to AE-O

conclusionCOPD patients who performed physical exercise associated with oxygen supplementation had a better response to DNA damage induced by MMS and a better DNA repair when compared to the condition of physical exercise without oxygen supplementation.

trial registrationUNISC N374.298. Registered 04 JUN 2013 (retrospectively registered).

Indexed as

Aerobic exerciseComet assayCOPDDNA repairInduced DNA damage

Identifiers

PMID28018592
PMCPMC5160001
OpenAlexW2564148981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.