ArticleFrontiers in microbiology2016
Do Bacterial "Virulence Factors" Always Increase Virulence? A Meta-Analysis of Pyoverdine Production in
Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Trojan Horses: Conjugating Siderophores and Antibiotics-A New Approach to TreatingMicroorganisms · 2026Review
- Taming Superbugs: Current Progress and Challenges in Combating ESKAPE Pathogens.Pathogens (Basel, Switzerland) · 2025Review
- Bacterial infections and pathogenic situations: The case ofVirulence · 2025Review
- Quorum Sensing Inhibition by Sponge-AssociatedAntibiotics (Basel, Switzerland) · 2025Article
- Iron acquisition strategies in pseudomonads: mechanisms, ecology, and evolution.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023Review
- The effect of metal remediation on the virulence and antimicrobial resistance of the opportunistic pathogenEvolutionary applications · 2023Article
- Copper selects for siderophore-mediated virulence in Pseudomonas aeruginosa.BMC microbiology · 2022Article
- Article
- Functional Analysis of Hypothetical Proteins ofBioinformatics and biology insights · 2022Article
- Loss of a pyoverdine secondary receptor in Pseudomonas aeruginosa results in a fitter strain suitable for population invasion.The ISME journal · 2021Article
- The Vibriolysin-Like Protease VnpA and the Collagenase ColA Are Required for Full Virulence of the Bivalve Mollusks PathogenAntibiotics (Basel, Switzerland) · 2021Article
- Molecular Analysis of the Contribution of Alkaline Protease A and Elastase B to the Virulence ofFrontiers in cellular and infection microbiology · 2021Article
- Bacterial siderophores in community and host interactions.Nature reviews. Microbiology · 2020Review
- Harnessing bacterial interactions to manage infections: a review on the opportunistic pathogenJournal of medical microbiology · 2020Review
- Serological Testing for Mycobacterial Heat Shock ProteinMicroorganisms · 2019Article
- Pyoverdine-Dependent Virulence ofFrontiers in microbiology · 2019Article
- Probing the evolutionary robustness of two repurposed drugs targeting iron uptake inEvolution, medicine, and public health · 2018Article
- Optimised chronic infection models demonstrate that siderophore 'cheating' in Pseudomonas aeruginosa is context specific.The ISME journal · 2017Article
- Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens.Natural product reports · 2017Review
- High virulence sub-populations in Pseudomonas aeruginosa long-term cystic fibrosis airway infections.BMC microbiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial traits that contribute to disease are termed "virulence factors" and there is much interest in therapeutic approaches that disrupt such traits. What remains less clear is whether a virulence factor identified as such in a particular context is also important in infections involving different host and pathogen types. Here, we address this question using a meta-analytic approach. We statistically analyzed the infection outcomes of 81 experiments associated with one well-studied virulence factor-pyoverdine, an iron-scavenging compound secreted by the opportunistic pathogen
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.