Evidence map›Paper›PMID 28018238›Full record

ArticleFrontiers in physiology2016

Key Brainstem Structures Activated during Hypoxic Exposure in One-day-old Mice Highlight Characteristics for Modeling Breathing Network in Premature Infants.

Fanny Joubert, Camille Loiseau, Anne-Sophie Perrin-Terrin, Florence Cayetanot, Alain Frugière, Nicolas Voituron, Laurence Bodineau

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Whole-brain analysis of CObioRxiv : the preprint server for biology · 2023
    Article
  6. Article
  7. Prenatal Hypoxia Induces ClFrontiers in physiology · 2022
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Fanny JoubertSorbonne Universités, UPMC Univ Paris 06, Institut National de la Santé et de la Recherche Médicale, UMR_S1158 Neurophysiologie Respiratoire Expérimentale et Clinique Paris, France.
Camille LoiseauSorbonne Universités, UPMC Univ Paris 06, Institut National de la Santé et de la Recherche Médicale, UMR_S1158 Neurophysiologie Respiratoire Expérimentale et Clinique Paris, France.
Anne-Sophie Perrin-TerrinSorbonne Universités, UPMC Univ Paris 06, Institut National de la Santé et de la Recherche Médicale, UMR_S1158 Neurophysiologie Respiratoire Expérimentale et CliniqueParis, France; Sorbonne Paris Cité, Université Paris 13, EA2363 Hypoxie et PoumonsBobigny, France.
Florence CayetanotInstitut de Neurosciences de la Timone, Aix Marseille Université, Centre National de la Recherche Scientifique, UMR 7289 Marseille, France.
Alain FrugièreSorbonne Universités, UPMC Univ Paris 06, Institut National de la Santé et de la Recherche Médicale, UMR_S1158 Neurophysiologie Respiratoire Expérimentale et Clinique Paris, France.
Nicolas VoituronSorbonne Paris Cité, Université Paris 13, EA2363 Hypoxie et Poumons Bobigny, France.
Laurence BodineauSorbonne Universités, UPMC Univ Paris 06, Institut National de la Santé et de la Recherche Médicale, UMR_S1158 Neurophysiologie Respiratoire Expérimentale et Clinique Paris, France.
Neurophysiologie respiratoire expérimentale et cliniqueUniversité Sorbonne Paris Nord · FRAssistance Publique – Hôpitaux de Paris · FRInstitut de Neurosciences de la Timone · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We mapped and characterized changes in the activity of brainstem cell groups under hypoxia in one-day-old newborn mice, an animal model in which the central nervous system at birth is particularly immature. The classical biphasic respiratory response characterized by transient hyperventilation, followed by severe ventilation decline, was associated with increased c-FOS immunoreactivity in brainstem cell groups: the nucleus of the solitary tract, ventral reticular nucleus of the medulla, retrotrapezoid/parafacial region, parapyramidal group,

Indexed as

catecholaminec-FOShypoxic ventilatory depressionPHOX2Bserotoninsubcoeruleus nucleus

Identifiers

PMID28018238
PMCPMC5145891
OpenAlexW2560698860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.