ArticleWorld journal of gastroenterology2016
Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis.
Article in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Correlation of ammonia and blood laboratory parameters with hepatic encephalopathy: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Effect of non-alcoholic beer, diet and exercise on endothelial function, nutrition and quality of life in patients with cirrhosis.World journal of hepatology · 2020Trial
- Sarcopenia Is Associated With Mortality and Progression of Cirrhosis in Decompensated but Not Compensated Disease-A Multicentre Study.Alimentary pharmacology & therapeutics · 2026Article
- Zinc deficiency and sarcopenia define a metabolic frailty phenotype predicting hepatic encephalopathy and early mortality in cirrhosis.Metabolic brain disease · 2026Article
- Gut Dysbiosis, Malnutrition and Sarcopenia in Liver Cirrhosis: A Narrative Review.Diseases (Basel, Switzerland) · 2026Review
- Bioelectrical impedance analysis of body composition in children and adolescents with type 1 diabetes: a prospective case-control study.European journal of pediatrics · 2025Article
- A GLIM-defined malnutrition-based model for predicting prognosis of cirrhotic patients with portal hypertension following TIPS procedure.BMC gastroenterology · 2025Article
- Bioelectrical impedance analysis-derived phase angle predicts osteosarcopenia and mortality in patients with chronic liver disease.Scientific reports · 2025Article
- [Assessment and management of malnutrition in patients with cirrhosis combined with hepatic encephalopathy].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Review
- Hepatic encephalopathy: risk identification and prophylaxis approaches.Metabolic brain disease · 2025Review
- Phase angle associates with severity and mortality in acute-on-chronic liver failure.Frontiers in medicine · 2025Article
- Quantitative Assessment of Body Composition in Cirrhosis.Diagnostics (Basel, Switzerland) · 2024Review
- Optimizing nutrition in hepatic cirrhosis: A comprehensive assessment and care approach.World journal of gastroenterology · 2024Review
- Nutritional Support for Liver Diseases.Nutrients · 2023Review
- Unlocking the Power of Late-Evening Snacks: Practical Ready-to-Prescribe Chart Menu for Patients with Cirrhosis.Nutrients · 2023Review
- Myostatin is associated with the presence and development of acute-on-chronic liver failure.JHEP reports : innovation in hepatology · 2023Article
- Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis.Nutrients · 2023Article
- The use of phase angle in patients with digestive and liver diseases.Reviews in endocrine & metabolic disorders · 2023Review
- Nutritional assessment in patients with liver cirrhosis.World journal of hepatology · 2022Review
- Nutritional therapy for hepatocellular carcinoma.World journal of gastrointestinal oncology · 2021Review
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimEvaluate the association between phase angle and the development of hepatic encephalopathy in the long-term follow-up of cirrhotic patients.
methodsThis was a prospective cohort study. Clinical, nutritional and biochemical evaluations were performed. Mann-Whitney's
resultsTwo hundred and twenty were included; the most frequent etiology of cirrhosis was hepatitis C infection, 52% of the patients developed hepatic encephalopathy (18.6% covert and 33.3% overt); the main precipitating factors were infections and variceal bleeding. Kaplan-Meier curves showed a higher proportion of HE in the group with low phase angle (39%) compared to the normal phase angle group (13%) (
conclusionIn our cohort of patients low phase angle was associated with an increased incidence of hepatic encephalopathy. Phase angle is a useful nutritional marker that evaluates cachexia and could be used as a part of the integral assessment in patients with cirrhosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.