Evidence map›Paper›PMID 28017433›Full record

ArticleVaccine2017

Passive antibodies derived from intramuscularly immunized toxoid fusion 3xSTa

Rahul M Nandre, Qiangde Duan, Yin Wang, Weiping Zhang

Abstract read
In one paragraph

Article in Vaccine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Recent progress in enterotoxigenicInfection and immunity · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Pig vaccination strategies based on enterotoxigenic Escherichia coli toxins.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Adjuvant effect of enterotoxigenicHuman vaccines & immunotherapeutics · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rahul M NandreDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, KS 66506, USA.
Qiangde DuanDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, KS 66506, USA.
Yin WangDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, KS 66506, USA.
Weiping ZhangDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, KS 66506, USA. Electronic address: wpzhang@vet.k-state.edu.
Kansas State University · US

Funding

A broadly protective subunit vaccine against enterotoxigenic Escherichia coli (ETEC) associateddiarrheaR01AI121067 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ZHANG, WEIPING · 2016 to 2020
$2.0M
A subunit vaccine for enterotoxigenic E. coli associated traveler's diarrheaR21AI109209 · NIAID · KANSAS STATE UNIVERSITY · PI ZHANG, WEIPING · 2014 to 2015
$413k
NIAID NIH HHS R01 AI121067NIAID NIH HHS R21 AI109209
6 · The paper itself

Abstract

Enterotoxigenic Escherichia coli (ETEC) strains are among the most common causes of children's diarrhea and travelers' diarrhea. Developing effective vaccines against ETEC associated diarrhea becomes a top priority. ETEC heat-labile toxin (LT) and heat-stable toxin (STa) toxoid fusion 3xSTa

Indexed as

Immunity, Maternally-AcquiredAnimalsAntibodies, BacterialBacterial ToxinsDiarrheaEnterotoxigenic Escherichia coliEnterotoxinsEscherichia coli InfectionsEscherichia coli ProteinsEscherichia coli VaccinesFemaleImmunoglobulin AImmunoglobulin GInjections, IntramuscularPregnancySwineAntibodies, BacterialBacterial ToxinsEnterotoxinsEscherichia coli ProteinsEscherichia coli Vaccinesheat-labile enterotoxin, E coliheat stable toxin (E coli)Immunoglobulin AImmunoglobulin G3xSTa(N12S)-dmLTDiarrheaEnterotoxigenic Escherichia coli (ETEC)Pig challenge modelToxoid fusionVaccine

Identifiers

PMID28017433
PMCPMC5261774
OpenAlexW2566734708

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.