Evidence map›Paper›PMID 28013460›Full record

ArticleEnvironmental science and pollution research international2017

Arsenic trioxide induces ROS activity and DNA damage, leading to G0/G1 extension in skin fibroblasts through the ATM-ATR-associated Chk pathway.

Jutapon Chayapong, Harishkumar Madhyastha, Radha Madhyastha, Queen Intan Nurrahmah, Yuichi Nakajima, Narantsog Choijookhuu, Yoshitaka Hishikawa, Masugi Maruyama

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
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  7. Article
  8. Arsenic Impairs Wound Healing Processes in Dermal Fibroblasts and Mice.International journal of molecular sciences · 2024
    Article
  9. Review
  10. Arsenic and cancer: Evidence and mechanisms.Advances in pharmacology (San Diego, Calif.) · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Effect of arsenic trioxide on cervical cancer and its mechanisms.Experimental and therapeutic medicine · 2020
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jutapon ChayapongDepartment of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Harishkumar MadhyasthaDepartment of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.ORCID http://orcid.org/0000-0002-7143-4821
Radha MadhyasthaDepartment of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Queen Intan NurrahmahDepartment of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Yuichi NakajimaDepartment of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Narantsog ChoijookhuuDepartment of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Yoshitaka HishikawaDepartment of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan.
Masugi MaruyamaDepartment of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan. masugi@med.miyazaki-u.ac.jp.
University of Miyazaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arsenic (As) toxicity is a global health problem, affecting millions of people. Exposure to arsenic, mostly via drinking water, has been associated with cancer of skin, lungs, and blood, in addition to several kinds of skin lesions. The present study focused on the effect of arsenic trioxide (As

Indexed as

DNA DamageArsenicalsArsenic TrioxideCell CycleCell Cycle CheckpointsCell DivisionCell Line, TumorEnvironmental PollutantsFibroblastsHumansOxidesSignal TransductionArsenicalsArsenic TrioxideEnvironmental PollutantsOxidesArsenic trioxideCell cycle arrestDNA damageG0/G1

Identifiers

PMID28013460
OpenAlexW2564185159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.