Evidence map›Paper›PMID 28013420›Full record

ArticlePrevention science : the official journal of the Society for Prevention Research2018

Two-Year Impact of Prevention Programs on Adolescent Depression: an Integrative Data Analysis Approach.

C Hendricks Brown, Ahnalee Brincks, Shi Huang, Tatiana Perrino, Gracelyn Cruden, Hilda Pantin, George Howe, Jami F Young, William Beardslee, Samantha Montag and 1 more

Abstract read
In one paragraph

Article in Prevention science : the official journal of the Society for Prevention Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Tri-sector Partnership for Military Suicide Prevention: Developing, Testing, and Scaling Wingman Guardian Connect.Prevention science : the official journal of the Society for Prevention Research · 2026
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  9. Fusing Individualized Treatment Rules Using Secondary Outcomes.Proceedings of machine learning research · 2024
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  12. Retrospective Psychometrics and Effect Heterogeneity in Integrated Data Analysis: Commentary on the Special Issue.Prevention science : the official journal of the Society for Prevention Research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

C Hendricks BrownDepartments of Psychiatry and Behavioral Sciences, Preventive Medicine, and Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. hendricks.brown@northwestern.edu.ORCID 0000-0002-0294-2419
Ahnalee BrincksDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
Shi HuangDepartment of Biostatistics, Vanderbilt University, Nashville, TN, USA.
Tatiana PerrinoDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Gracelyn CrudenDepartments of Psychiatry and Behavioral Sciences, Preventive Medicine, and Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Hilda PantinDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
George HoweDepartments of Psychology and Psychiatry and Behavioral Sciences, George Washington University, Washington, DC, USA.
Jami F YoungGraduate School of Applied and Professional Psychology, Rutgers University, New Brunswick, NJ, USA.
William BeardsleeBoston Children's Hospital, Harvard University, Cambridge, MA, USA.
Samantha MontagDepartments of Psychiatry and Behavioral Sciences, Preventive Medicine, and Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Irwin SandlerDepartment of Psychology, Arizona State University, Tempe, AZ, USA.
Northwestern University · USUniversity of Miami · USArizona State University · USBoston Children's Hospital · USGeorge Washington University · USRutgers, The State University of New Jersey · USVanderbilt University · US

Funding

STATISTICAL METHODS FOR MENTAL HEALTH PREVENTIVE TRIALSR01MH040859 · NIMH · UNIVERSITY OF SOUTH FLORIDA · PI BROWN, C. HENDRICKS · 1986 to 2014
$7.5M
UNDERSTANDING AND PREVENTING ADOLESCENT DRUG ABUSER37DA007031 · NIDA · UNIVERSITY OF OREGON · PI DISHION, THOMAS J · 1997 to 2005
$7.2M
ASU Prevention Research Center for Families in StressP30MH068685 · NIMH · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SANDLER, IRWIN N. · 2005 to 2010
$7.0M
Preventive Intervention for Mexican American AdolescentsR01MH064707 · NIMH · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI GONZALES, NANCY A. · 2001 to 2011
$6.8M
Understanding and Preventing Early Adult Drug AbuseR01DA007031 · NIDA · UNIVERSITY OF OREGON · PI LEMERY-CHALFANT, KATHRYN · 1991 to 2015
$6.2M
Impact of the Family Bereavement Program Fifteen Years LaterR01MH049155 · NIMH · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI AYERS, TIM S, SANDLER, IRWIN N. · 1994 to 2014
$6.1M
Multi-Court Trial of NBP to Prevent Substance Abuse and Mental Health DisorderR01DA026874 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SANDLER, IRWIN N. · 2011 to 2015
$6.0M
Evaluating the Effectiveness of an eHealth EBI for Latino Youth in Primary CareR01DA040756 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PRADO, GUILLERMO · 2016 to 2020
$3.9M
Prevention of Depression in At-Risk AdolescentsR01MH064503 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRENT, DAVID A. · 2003 to 2012
$3.9M
CORE--TRAININGP30MH039246 · NIMH · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MILLSAP, ROGER E · 1995 to 2002
$3.9M
A Family Intervention for Adolescent Problem BehaviorR01DA018374 · NIDA · UNIVERSITY OF OREGON · PI STORMSHAK, ELIZABETH A · 2005 to 2009
$3.2M
Primary Care Internet-Based Depression Prevention for Adolescents (CATCH-IT)R01MH090035 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GLADSTONE, TRACY G, VAN VOORHEES, BENJAMIN W · 2011 to 2015
$3.2M
NCHHSTP CDC HHS U01 PS000671NIDA NIH HHS R01 DA007031NIDA NIH HHS R01 DA017462NIDA NIH HHS R01 DA018374NIDA NIH HHS R01 DA025894NIDA NIH HHS R01 DA026874NIDA NIH HHS R01 DA040756NIDA NIH HHS R37 DA007031NIMH NIH HHS K08 MH072918NIMH NIH HHS K23 MH071320NIMH NIH HHS P30 MH039246NIMH NIH HHS P30 MH068685NIMH NIH HHS R01 MH040859NIMH NIH HHS R01 MH049155NIMH NIH HHS R01 MH052270NIMH NIH HHS R01 MH064503NIMH NIH HHS R01 MH064707NIMH NIH HHS R01 MH064717NIMH NIH HHS R01 MH064735NIMH NIH HHS R01 MH090035William T. Grant Foundation 961730
6 · The paper itself

Abstract

This paper presents the first findings of an integrative data analysis of individual-level data from 19 adolescent depression prevention trials (n = 5210) involving nine distinct interventions across 2 years post-randomization. In separate papers, several interventions have been found to decrease the risk of depressive disorders or elevated depressive/internalizing symptoms among youth. One type of intervention specifically targets youth without a depressive disorder who are at risk due to elevated depressive symptoms and/or having a parent with a depressive disorder. A second type of intervention targets two broad domains: prevention of problem behaviors, which we define as drug use/abuse, sexual risk behaviors, conduct disorder, or other externalizing problems, and general mental health. Most of these latter interventions improve parenting or family factors. We examined the shared and unique effects of these interventions by level of baseline youth depressive symptoms, sociodemographic characteristics of the youth (age, sex, parent education, and family income), type of intervention, and mode of intervention delivery to the youth, parent(s), or both. We harmonized eight different measures of depression utilized across these trials and used growth models to evaluate intervention impact over 2 years. We found a significant overall effect of these interventions on reducing depressive symptoms over 2 years and a stronger impact among those interventions that targeted depression specifically rather than problem behaviors or general mental health, especially when baseline symptoms were high. Implications for improving population-level impact are discussed.

Indexed as

Health PromotionAdolescentCognitive Behavioral TherapyData AnalysisDepressionFemaleHumansMaleOutcome Assessment, Health CareParentingParentsCognitive behavioral therapyData synthesisGrowth mixture modelingGrowth modelingInterpersonal therapyParenting interventionsPerson-level meta-analysis

Identifiers

PMID28013420
PMCPMC5483191
OpenAlexW2565795563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.