ArticleCancer epidemiology2017
Risk of malignant childhood germ cell tumors in relation to demographic, gestational, and perinatal characteristics.
Article in Cancer epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Pooled it
- Article
- Parental occupation and childhood germ cell tumors: a case-control study in Denmark, 1968-2016.Cancer causes & control : CCC · 2021Article
- Occupational livestock or animal dust exposure and offspring cancer risk in Denmark, 1968-2016.International archives of occupational and environmental health · 2020Article
- Phototherapy and childhood cancer: Shared risk factors.International journal of cancer · 2020Article
- Prenatal Exposure to Air Toxics and Malignant Germ Cell Tumors in Young Children.Journal of occupational and environmental medicine · 2019Article
- Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group.British journal of cancer · 2018Article
- Congenital neurodevelopmental anomalies in pediatric and young adult cancer.American journal of medical genetics. Part A · 2017Article
- Exposure to ambient dichloromethane in pregnancy and infancy from industrial sources and childhood cancers in California.International journal of hygiene and environmental health · 2017Article
- Maternal Preeclampsia and Odds of Childhood Cancers in Offspring: A California Statewide Case-Control Study.Paediatric and perinatal epidemiology · 2017Article
- A 10-year retrospective study of the risks and peculiarities in pediatric patients with (para)gonadal tumors and cysts.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundChildhood germ cell tumors (GCTs) are a rare assortment of neoplasms, with mostly unknown etiology, that are believed to originate very early in life. Few studies have examined risk factors by histologic subtype, despite evidence of different risk profiles. MATERIALS AND
methodsIn this population-based case-control study, 451 childhood malignant GCT cases ages 0-5 years were identified from the California Cancer Registry. Differentiating between common histologic subtypes, we identified 181 yolk sac tumors, 216 teratomas, and 54 rarer subtypes. Cases were linked to their birth certificates and 271,381 controls, frequency matched by birth year, were randomly selected from California birthrolls to investigate the contributions of demographic, gestational, and pregnancy factors using unconditional logistic regression analysis.
resultsCompared to non-Hispanic whites, Asian/Pacific Islander children were at an increased risk for developing GCTs (odds ratio [OR]=1.94; 95% confidence interval [CI]=1.47, 2.56). Among pregnancy complications and procedures, yolk sac tumors were positively associated with the presence of fetopelvic disproportion (OR=2.97; 95% CI=1.55, 5.68), while teratomas were strongly associated with polyhydramnios or oligohydramnios (OR=14.76; 95% CI=7.21, 30.19) and the presence of an ear, face, or neck anomaly at birth (OR=93.70; 95% CI=42.14, 208.82).
conclusionsMalignant yolk sac tumors and malignant teratomas exhibited distinct demographic and gestational characteristics; additionally, complications in pregnancy and labor may be brought on by specific histologic subtypes.
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