Evidence map›Paper›PMID 28012878›Full record

ReviewSurvey of ophthalmology

Viral posterior uveitis.

Joanne H Lee, Aniruddha Agarwal, Padmamalini Mahendradas, Cecilia S Lee, Vishali Gupta, Carlos E Pavesio, Rupesh Agrawal

Abstract readReview
In one paragraph

Review in Survey of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Joanne H LeeYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Aniruddha AgarwalDepartment of Vitreoretina and Uveitis, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Padmamalini MahendradasDepartment of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, India.
Cecilia S LeeDepartment of Uveitis, University of Washington, Seattle, Washington, USA.
Vishali GuptaDepartment of Vitreoretina and Uveitis, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Carlos E PavesioDepartment of Medical Retina, Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom.
Rupesh AgrawalYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Department of Medical Retina, Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom; Department of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore. Electronic address: rupesh_agrawal@ttsh.com.sg.
Moorfields Eye Hospital NHS Foundation Trust · GBPost Graduate Institute of Medical Education and Research · INNarayana Nethralaya · INNational University of Singapore · SGUniversity of Washington · US

Funding

The ocular surface microbiome in potentially infectious ophthalmic diseaseK23EY024921 · NEI · UNIVERSITY OF WASHINGTON · PI LEE, CECILIA SUNGMIN · 2015 to 2019
$991k
NEI NIH HHS K23 EY024921
6 · The paper itself

Abstract

The causes of posterior uveitis can be divided into infectious, autoimmune, or masquerade syndromes. Viral infections, a significant cause of sight-threatening ocular diseases in the posterior segment, include human herpesviruses, measles, rubella, and arboviruses such as dengue, West Nile, and chikungunya virus. Viral posterior uveitis may occur as an isolated ocular disease in congenital or acquired infections or as part of a systemic viral illness. Many viruses remain latent in the infected host with a risk of reactivation that depends on various factors, including virulence and host immunity, age, and comorbidities. Although some viral illnesses are self-limiting and have a good visual prognosis, others, such as cytomegalovirus retinitis or acute retinal necrosis, may result in serious complications and profound vision loss. Since some of these infections may respond well to antiviral therapy, it is important to work up all cases of posterior uveitis to rule out an infectious etiology. We review the clinical features, diagnostic tools, treatment regimens, and long-term outcomes for each of these viral posterior uveitides.

Indexed as

Diagnostic Techniques, OphthalmologicalEye Infections, ViralUveitis, PosteriorGlobal HealthHumansMorbidityCMV retinitisherpetic retinitispolymerase chain reactionposterior uveitisviral posterior uveitisviruses

Identifiers

PMID28012878
PMCPMC5654632
OpenAlexW2566137062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.