Evidence map›Paper›PMID 28012718›Full record

ArticleThe Journal of investigative dermatology2017

Skin-Resident Effector Memory CD8

Gang Li, Adriana T Larregina, Robyn T Domsic, Donna B Stolz, Thomas A Medsger, Robert Lafyatis, Patrizia Fuschiotti

Abstract read
In one paragraph

Article in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. CD8MedComm · 2026
    Review
  3. Article
  4. Article
  5. Evolving role of CD8Frontiers in immunology · 2026
    Review
  6. Radioresistance Mechanisms in Head and Neck Cancer.Clinical and experimental otorhinolaryngology · 2025
    Review
  7. [Exploring the Causal Relationship Between Circulating Immune Cells and Autoimmune Hepatitis Through Mendelian Randomization Analysis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. CD8International journal of molecular sciences · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. The expanding impact of T-regs in the skin.Frontiers in immunology · 2022
    Review
  20. Harnessing CD8Cells · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gang LiDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Adriana T LarreginaDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Robyn T DomsicDepartment of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Donna B StolzDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Thomas A MedsgerDepartment of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Robert LafyatisDepartment of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Patrizia FuschiottiDepartment of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: paf23@pitt.edu.
University of Pittsburgh · US

Funding

Pathogenesis of systemic sclerosis: role of the skin-resident CD8+ T cellsR03AR065755 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FUSCHIOTTI, PATRIZIA · 2014 to 2016
$231k
NIAMS NIH HHS R03 AR065755
6 · The paper itself

Abstract

Loss of CD28 expression by CD8

Indexed as

AdultAgedCase-Control StudiesCD28 AntigensCD8-Positive T-LymphocytesCollagenFemaleFibrosisHumansInterleukin-13MaleMiddle AgedPhenotypeScleroderma, SystemicSkinYoung AdultCD28 AntigensCollagenInterleukin-13

Identifiers

PMID28012718
PMCPMC5433864
OpenAlexW2561965154

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.