Evidence map›Paper›PMID 28012037›Full record

ArticleEuropean journal of applied physiology2017

Differentiating swelling and hypertrophy through indirect assessment of muscle damage in untrained men following repeated bouts of resistance exercise.

Samuel L Buckner, Scott J Dankel, Kevin T Mattocks, Matthew B Jessee, J Grant Mouser, Brittany R Counts, Gilberto C Laurentino, Jeremy P Loenneke

Abstract read
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Article in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samuel L BucknerKevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, P.O. Box 1848, University, MS, 38677, USA.
Scott J DankelKevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, P.O. Box 1848, University, MS, 38677, USA.
Kevin T MattocksKevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, P.O. Box 1848, University, MS, 38677, USA.
Matthew B JesseeKevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, P.O. Box 1848, University, MS, 38677, USA.
J Grant MouserKevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, P.O. Box 1848, University, MS, 38677, USA.
Brittany R CountsKevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, P.O. Box 1848, University, MS, 38677, USA.
Gilberto C LaurentinoKevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, P.O. Box 1848, University, MS, 38677, USA.
Jeremy P LoennekeKevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, P.O. Box 1848, University, MS, 38677, USA. jploenne@olemiss.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the swelling response and other markers of muscle damage throughout the early portions of a training program (Experiment 1). We also determined if a "swollen" muscle could swell further following additional exercise (Experiment 2).

methodsNine males performed four sets of biceps curls (or time-matched rest on control arm) at 70% of their one-repetition maximum three times over 8 days. Muscle thickness and torque were measured before and after exercise as well as on the days in between. Soreness was measured at the beginning of each day (Experiment 1). On the final day (Experiment 2), participants performed two bouts of exercise, followed by additional measures of muscle thickness.

resultsFollowing three bouts of exercise, muscle thickness was elevated over baseline (mean of visit 9 pre to visit 2 pre, 95% CI) at the 50% [0.21 (0.07, 0.34) cm], 60% [0.21 (0.02, 0.39) cm], and 70% [0.21 (0.06, 0.36) cm] sites. However, differences from a non-exercise control were only observed immediately following bouts of exercise (indicative of acute swelling). Torque was lower at every time point following the first bout of exercise and remained suppressed relative to pre at visit 9 [-6.1 (-11.7, -0.47 Nm] in the experimental arm. Experiment 2 found that a swollen muscle could not appreciably swell more.

conclusionResting levels of muscle thickness do not appear to change beyond what occurs following the first naïve bout of exercise. Also, the acute swelling response may be used to differentiate swelling from muscle growth.

Indexed as

ExerciseMuscle ContractionAdultArmHumansMaleMuscle, SkeletalMuscle StrengthMyalgiaRandom AllocationTorqueEdemaMuscle growthSwelling

Identifiers

PMID28012037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.