Evidence map›Paper›PMID 28011993›Full record

ArticleCurrent genetics2017

Putative orotate transporter of Cryptococcus neoformans, Oat1, is a member of the NCS1/PRT transporter super family and its loss causes attenuation of virulence.

Akio Toh-E, Misako Ohkusu, Kiminori Shimizu, Azusa Takahashi-Nakaguchi, Susumu Kawamoto, Naruhiko Ishiwada, Akira Watanabe, Katsuhiko Kamei

Abstract read
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In one paragraph

Article in Current genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Akio Toh-EMedical Mycology Research Center, Chiba University, 1-8-1 Inohana, Chiba, 260-8673, Japan. toh-e@faculty.chiba-u.jp.
Misako OhkusuMedical Mycology Research Center, Chiba University, 1-8-1 Inohana, Chiba, 260-8673, Japan.
Kiminori ShimizuMedical Mycology Research Center, Chiba University, 1-8-1 Inohana, Chiba, 260-8673, Japan.
Azusa Takahashi-NakaguchiMedical Mycology Research Center, Chiba University, 1-8-1 Inohana, Chiba, 260-8673, Japan.
Susumu KawamotoMedical Mycology Research Center, Chiba University, 1-8-1 Inohana, Chiba, 260-8673, Japan.
Naruhiko IshiwadaMedical Mycology Research Center, Chiba University, 1-8-1 Inohana, Chiba, 260-8673, Japan.
Akira WatanabeMedical Mycology Research Center, Chiba University, 1-8-1 Inohana, Chiba, 260-8673, Japan.
Katsuhiko KameiMedical Mycology Research Center, Chiba University, 1-8-1 Inohana, Chiba, 260-8673, Japan.
Chiba University Hospital · JPTokyo University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well known that 5-fluoroorotic acid (5-FOA)-resistant mutants isolated from wild-type Cryptococcus neoformans are exclusively either ura3 or ura5 mutants. Unexpectedly, many of the 5-FOA-resistant mutants isolated in our selective regime were Ura

Indexed as

Biological TransportCryptococcus neoformansGene Expression Regulation, FungalMembrane Transport ProteinsMutationNitrogenOrotic AcidUracil5-fluoroorotic acidMembrane Transport ProteinsNitrogenOrotic AcidUracil5-FOANitrogen metabolite repressionOrotate permeasePyrimidine pathway

Identifiers

PMID28011993
OpenAlexW2566170061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.