ArticleArchives of toxicology2017
Hair analysis for the biomonitoring of pesticide exposure: comparison with blood and urine in a rat model.
Article in Archives of toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 99 citations in OpenAlex.
- Not just splitting hairs-monitoring environmental chemical exposures, their biological effects and their social determinants with hair shafts and follicles: a narrative review.Environmental health : a global access science source · 2026Review
- Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay.Drug testing and analysis · 2026Article
- Multiclass Assays for Measuring Environmental Chemical Mixture Exposure: Analytical Methodologies and Applications in Exposomics Research.Metabolites · 2025Review
- Hair-Derived Exposome Exploration of Cardiometabolic Health: Piloting a Bayesian Multitrait Variable Selection Approach.Environmental science & technology · 2024Article
- In Vitro Effects of Cypermethrin and Glyphosate on LPS-Induced Immune Cell Activation.Life (Basel, Switzerland) · 2023Article
- Association between pyrethroid exposure and osteoarthritis: a national population-based cross-sectional study in the US.BMC public health · 2023Article
- Validation of a Method Scope Extension for Simple Biomonitoring of 353 Pollutants in Serum Samples.Toxics · 2023Article
- Rapid LC-MS/MS quantification of Organophosphate non-specific metabolites in hair using alkaline extraction approach.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2023Article
- Pervasive exposure of wild small mammals to legacy and currently used pesticide mixtures in arable landscapes.Scientific reports · 2022Article
- Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru.Scientific reports · 2022Observational
- The Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-Chemical research in toxicology · 2022Review
- Article
- Multi-omics analysis to decipher the molecular link between chronic exposure to pollution and human skin dysfunction.Scientific reports · 2021Article
- Sample preparation method for metal(loid) contaminant quantitation in rodent hair collected in Yuma County, Arizona.Environmental monitoring and assessment · 2021Article
- Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis.International journal of environmental research and public health · 2021Article
- Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides.Journal of Alzheimer's disease : JAD · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urine and plasma have been used to date for the biomonitoring of exposure to pollutants and are still the preferred fluids for this purpose; however, these fluids mainly provide information on the short term and may present a high level of variability regarding pesticide concentrations, especially for nonpersistent compounds. Hair analysis may provide information about chronic exposure that is averaged over several months; therefore, this method has been proposed as an alternative to solely relying on these fluids. Although the possibility of detecting pesticides in hair has been demonstrated over the past few years, the unknown linkage between exposure and pesticides concentration in hair has limited the recognition of this matrix as a relevant tool for assessing human exposure. Based on a rat model in which there was controlled exposure to a mixture of pesticides composed of lindane, β-hexachlorocyclohexane, β-endosulfan, p,p'-DDT, p,p'-DDE, dieldrin, pentachlorophenol, diazinon, chlorpyrifos, cyhalothrin, permethrin, cypermethrin, propiconazole, fipronil, oxadiazon, diflufenican, trifluralin, carbofuran, and propoxur, the current work demonstrates the association between exposure intensity and resulting pesticide concentration in hair. We also compared the results obtained from a hair analysis to urine and plasma collected from the same rats. Hair, blood, and urine were collected from rats submitted to 90-day exposure by gavage to the aforementioned mixture of common pesticides at different levels. We observed a linear relationship between exposure intensity and the concentration of pesticides in the rats' hair (R
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