Evidence map›Paper›PMID 28011924›Full record

ArticleTobacco control2017

Childhood secondhand smoke exposure and pregnancy loss in never smokers: the Guangzhou Biobank Cohort Study.

Shanshan Yang, Lin Xu, Yao He, Chaoqiang Jiang, Yali Jin, Kar Keung Cheng, Weisen Zhang, Tai Hing Lam

Open access · hybridAbstract read
In one paragraph

Article in Tobacco control, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Shanshan YangInstitute of Geriatrics, Chinese PLA General Hospital, Beijing, China.
Lin XuSchool of Public Health, the University of Hong Kong, Hong Kong, China.
Yao HeInstitute of Geriatrics, Chinese PLA General Hospital, Beijing, China.
Chaoqiang JiangGuangzhou Number 12 People's Hospital, Guangzhou, China.
Yali JinGuangzhou Number 12 People's Hospital, Guangzhou, China.
Kar Keung ChengPublic Health, Epidemiology and Biostatistics, University of Birmingham, Birmingham, UK.
Weisen ZhangGuangzhou Number 12 People's Hospital, Guangzhou, China.
Tai Hing LamInstitute of Geriatrics, Chinese PLA General Hospital, Beijing, China.
Twelfth Guangzhou City People's Hospital · CNChinese PLA General Hospital · CNUniversity of Hong Kong · HKUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveStudies of secondhand smoke (SHS) exposure especially childhood SHS exposure and pregnancy loss are limited. We used baseline data of the Guangzhou Biobank Cohort Study (GBCS) to examine the association of childhood SHS exposure with a history of pregnancy loss.

methodsNever smoking women aged 50 years or above in GBCS from 2003 to 2008 were included. Propensity score matching (PSM) was used to control for confounding. Negative binomial regression and logistic regression were used to examine the association of childhood SHS, assessed by number of smokers in childhood household and frequency of exposure, with past pregnancy loss.

resultsOf 19 562 women, 56.7% (11 096) had SHS exposure during childhood. In negative binomial regression, after adjusting for age, education, past occupational dust exposure, past home fuel exposure, oral contraceptive, adulthood SHS exposure, age at first pregnancy and age at first menarche, compared to non-exposure, the incidence rate ratio of one more pregnancy loss was 1.20 (95% CI1.05 to 1.37) in those who lived with ≥2 smokers in the same household, and 1.14 (95% CI 1.04 to 1.25) in those exposed ≥5 times/week. After similar adjustment, logistic regression showed that the OR of pregnancy loss ≥2 times (versus 0 to 1 time) was 1.25 (95% CI 1.00 to 1.57) and 1.20 (95% CI 1.03 to 1.40) for high density (≥2 smokers in the same household) and frequency (≥5 times/week) of childhood exposure, respectively.

conclusionsChildhood SHS exposure was associated with higher risks of pregnancy loss in middle-aged and older Chinese women.

Indexed as

Abortion, SpontaneousAge FactorsBiological Specimen BanksChinaCohort StudiesFemaleHumansMiddle AgedPregnancyTobacco Smoke PollutionTobacco Smoke PollutionLow/Middle income countryPriority/special populationsSecondhand smoke

Identifiers

PMID28011924
PMCPMC5661265
OpenAlexW2563072655

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.