Evidence map›Paper›PMID 28011589›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2017

Maternal-engineered nanomaterial exposure disrupts progeny cardiac function and bioenergetics.

Quincy A Hathaway, Cody E Nichols, Danielle L Shepherd, Phoebe A Stapleton, Sarah L McLaughlin, Janelle C Stricker, Stephanie L Rellick, Mark V Pinti, Alaeddin B Abukabda, Carroll R McBride and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 71 citations in OpenAlex.

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  12. NNanotoxicology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Quincy A HathawayDivision of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Cody E NicholsDivision of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Danielle L ShepherdDivision of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Phoebe A StapletonDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia.
Sarah L McLaughlinDepartment of Cancer Cell Biology, West Virginia University School of Medicine; Morgantown, West Virginia; and.
Janelle C StrickerDivision of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Stephanie L RellickDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia.
Mark V PintiDivision of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Alaeddin B AbukabdaDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia.
Carroll R McBrideDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia.
Jinghai YiDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia.
Seth M StineDivision of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.
Timothy R NurkiewiczDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia.
John M HollanderDivision of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia; jhollander@hsc.wvu.edu.
West Virginia University · US

Funding

West Virginia University Stroke COBREP20GM109098 · NIGMS · WEST VIRGINIA UNIVERSITY · PI HRUSKA, MARTIN · 2014 to 2024
$24.5M
miRNA Regulation of the Mitochondrial GenomeR01HL128485 · NHLBI · WEST VIRGINIA UNIVERSITY · PI HOLLANDER, JOHN M · 2017 to 2019
$1.3M
Mitochondrial Mechanisms, Microvascular Function, and Gestational NanotoxicologyR00ES024783 · NIEHS · RUTGERS, THE STATE UNIV OF N.J. · PI STAPLETON, PHOEBE · 2017 to 2019
$747k
Visual Sonics Vevo 2100 Imaging SystemS10RR026378 · NCRR · WEST VIRGINIA UNIVERSITY · PI MARTIN, KAREN H · 2010 to 2010
$454k
miRNA Regulation of the Mitochondrial GenomeR56HL128485 · NHLBI · WEST VIRGINIA UNIVERSITY · PI HOLLANDER, JOHN M · 2015 to 2015
$410k
Mitochondrial Mechanisms, Microvascular Function, and Gestational NanotoxicologyK99ES024783 · NIEHS · WEST VIRGINIA UNIVERSITY · PI STAPLETON, PHOEBE · 2015 to 2016
$172k
NCRR NIH HHS S10 RR026378NHLBI NIH HHS R01 HL128485NHLBI NIH HHS R56 HL128485NIEHS NIH HHS K99 ES024783NIEHS NIH HHS R00 ES024783NIGMS NIH HHS P20 GM109098
6 · The paper itself

Abstract

Nanomaterial production is expanding as new industrial and consumer applications are introduced. Nevertheless, the impacts of exposure to these compounds are not fully realized. The present study was designed to determine whether gestational nano-sized titanium dioxide exposure impacts cardiac and metabolic function of developing progeny. Pregnant Sprague-Dawley rats were exposed to nano-aerosols (~10 mg/m

Indexed as

AgingAnimalsEchocardiographyElectron Transport Complex IElectron Transport Complex IVEnergy MetabolismFemaleHeartHeart DiseasesHeart Function TestsMyocardial ContractionMyocardiumMyocytes, CardiacNanostructuresPregnancyPrenatal Exposure Delayed EffectsElectron Transport Complex IElectron Transport Complex IVTitaniumtitanium dioxidecardiac dysfunctionmitochondriananomaterialspregnancy

Identifiers

PMID28011589
PMCPMC5402018
OpenAlexW2565162301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.