Evidence map›Paper›PMID 28011264›Full record

ArticleBrain, behavior, and immunity2017

Inflammation and exercise: Inhibition of monocytic intracellular TNF production by acute exercise via β

Stoyan Dimitrov, Elaine Hulteng, Suzi Hong

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Brain, behavior, and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06987708 (Evaluating the Impact of a 12-month Multi-Modal Lifestyle Management Intervention on Disease Relevant Biomarkers Associated With Monoclonal Gammopathy of Unknown Significance), which is not on this map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06987708 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluating the Impact of a 12-month Multi-Modal Lifestyle Management Intervention on Disease Relevant Biomarkers Associated With Monoclonal Gammopathy of Unknown Significance (MGUS) and Smoldering Myeloma (SM): A Prospective Intervention Pilot Study

TypeinterventionalSponsorHackensack Meridian HealthRan2026 to 2028Enrolled67ConditionsMonoclonal Gammopathy of Uncertain Significance, Smoldering MyelomaArmsThe Multimodal Lifestyle Intervention
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 120 citations in OpenAlex.

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  16. Functional Properties and Components of Koenigia alpina Extract.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  17. Frontal Alpha Asymmetry and Its Modulation by Monoaminergic Neurotransmitters in Depression.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stoyan DimitrovDepartment of Psychiatry, University of California, San Diego, USA.
Elaine HultengDepartment of Psychiatry, University of California, San Diego, USA.
Suzi HongDepartment of Psychiatry, University of California, San Diego, USA. Electronic address: suzihong@ucsd.edu.
University of California, San Diego · US

Funding

SAN DIEGO CLINICAL AND TRANSLATIONAL RESEARCH INSTITUTEUL1RR031980 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2010 to 2011
$14.0M
Role of obesity on vascular inflammation and immune cell activation in prehyperteR01HL090975 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HONG, SUZI · 2009 to 2013
$2.2M
NCRR NIH HHS UL1 RR031980NHLBI NIH HHS R01 HL090975
6 · The paper itself

Abstract

Regular exercise is shown to exert anti-inflammatory effects, yet the effects of acute exercise on cellular inflammatory responses and its mechanisms remain unclear. We tested the hypothesis that sympathoadrenergic activation during a single bout of exercise has a suppressive effect on monocytic cytokine production mediated by β

Indexed as

Adrenergic alpha-AgonistsAdrenergic beta-AgonistsAdultCytokinesEpinephrineExerciseFemaleHumansInflammationIsoproterenolMaleMiddle AgedMonocytesNorepinephrineTumor Necrosis Factor-alphaAdrenergic alpha-AgonistsAdrenergic beta-AgonistsCytokinesEpinephrineIsoproterenolNorepinephrineTumor Necrosis Factor-alphaAdrenergic agonistBeta blockerCytokine regulationExerciseSympathetic activation

Identifiers

PMID28011264
PMCPMC6555138
OpenAlexW2566213202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.