Evidence map›Paper›PMID 28011193›Full record

ArticleBrain research bulletin2018

Monitoring Ca

Olga Tyurikova, Kaiyu Zheng, Annika Rings, Anna Drews, David Klenerman, Dmitri A Rusakov

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain research bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Olga TyurikovaUCL Institute of Neurology, University College London, Queen Square, London WC1 3BG, UK; Institute of Neuroscience, University of Nizhny Novgorod, 603950 Nizhny Novgorod, Russia.
Kaiyu ZhengUCL Institute of Neurology, University College London, Queen Square, London WC1 3BG, UK.
Annika RingsUCL Institute of Neurology, University College London, Queen Square, London WC1 3BG, UK.
Anna DrewsDepartment of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
David KlenermanDepartment of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Dmitri A RusakovUCL Institute of Neurology, University College London, Queen Square, London WC1 3BG, UK. Electronic address: d.rusakov@ucl.ac.uk.
National Hospital for Neurology and Neurosurgery · GBUniversity of Cambridge · GBUniversity College London · GB

Funding

European Research Council 323113Medical Research Council G0600368Medical Research Council G0801316Medical Research Council G0802216Medical Research Council G0900613Wellcome Trust 101896Wellcome Trust 212251/Z/18/Z
6 · The paper itself

Abstract

The pathogenesis of Alzheimer's disease (AD) is thought to involve acute neurotoxic effects exerted by oligomeric forms of amyloid-β 1-42 (Aβ). Application of Aβ oligomers in physiological concentrations have been shown to transiently elevate internal Ca

Indexed as

Amyloid beta-PeptidesAnimalsAstrocytesCalciumCations, DivalentCentral Nervous System AgentsHippocampusMembrane PotentialsMicroscopy, FluorescenceNeuronsPatch-Clamp TechniquesPeptide FragmentsRats, Sprague-DawleySingle-Cell AnalysisTissue Culture TechniquesAmyloid beta-Peptidesamyloid beta-protein (1-42)CalciumCations, DivalentCentral Nervous System AgentsPeptide FragmentsAmyloid betaAstrogliaCalcium imagingFluorescence lifetime imagingHippocampus

Identifiers

PMID28011193
PMCPMC5766740
OpenAlexW2564824084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.