Evidence map›Paper›PMID 28009293›Full record

ArticleCell reports2016

Calcium Release from Stores Inhibits GIRK.

Paul F Kramer, John T Williams

Abstract read
In one paragraph

Article in Cell reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Reinventing amlodipine.The Journal of pharmacology and experimental therapeutics · 2026
    Review
  3. Review
  4. Article
  5. Neuronal G protein-gated KAmerican journal of physiology. Cell physiology · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. GeLife · 2018
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paul F KramerVollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.
John T WilliamsVollum Institute, Oregon Health and Science University, Portland, OR 97239, USA. Electronic address: williamj@ohsu.edu.

Funding

COCAINE: EFFECTS ON SINGLE NEURONSR01DA004523 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAMS, JOHN T · 1987 to 2025
$7.6M
PHOTOCHEMICAL REGULATION OF CALCIUM IN CELL PHYSIOLOGYR01GM053395 · NIGMS · OREGON HEALTH AND SCIENCE UNIVERSITY · PI ELLIS-DAVIES, GRAHAM · 1995 to 2020
$6.1M
Optical probes for controlling cellular functionR01NS069720 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ELLIS-DAVIES, GRAHAM · 2010 to 2017
$3.2M
NIDA NIH HHS R01 DA004523NIGMS NIH HHS R01 GM053395NINDS NIH HHS R01 NS069720
6 · The paper itself

Abstract

Synaptic transmission is mediated by ionotropic and metabotropic receptors that together regulate the rate and pattern of action potential firing. Metabotropic receptors can activate ion channels and modulate other receptors and channels. The present paper examines the interaction between group 1 mGluR-mediated calcium release from stores and GABA

Indexed as

Action PotentialsAnimalsCalciumCalmodulinDopamineDopaminergic NeuronsG Protein-Coupled Inwardly-Rectifying Potassium ChannelsProtein Kinase CRatsReceptors, Dopamine D2Receptors, GABA-BReceptors, Metabotropic GlutamateSubstantia NigraSynaptic TransmissionType C PhospholipasesCalciumCalmodulinDopamineG Protein-Coupled Inwardly-Rectifying Potassium Channelsmetabotropic glutamate receptor type 1Protein Kinase CReceptors, Dopamine D2Receptors, GABA-BReceptors, Metabotropic GlutamateType C PhospholipasescalciumD2dopamine neuronsGABA(B)GIRK inhibitiongroup I mGluRIP(3)

Identifiers

PMID28009293
PMCPMC5207023

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.