Evidence map›Paper›PMID 28009098›Full record

ArticleJournal of biophotonics2017

High-speed photoacoustic microscopy of mouse cortical microhemodynamics.

Li Lin, Junjie Yao, Ruiying Zhang, Chun-Cheng Chen, Chih-Hsien Huang, Yang Li, Lidai Wang, William Chapman, Jun Zou, Lihong V Wang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biophotonics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Li LinOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Junjie YaoOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Ruiying ZhangOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Chun-Cheng ChenDepartment of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Chih-Hsien HuangDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA.
Yang LiOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Lidai WangOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
William ChapmanDepartment of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Jun ZouDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA.
Lihong V WangOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Washington University in St. Louis · USCity University of Hong Kong · HKDuke University · USTexas A&M University · US

Funding

IN VIVO IMAGING OF SINGLE CIRCULATING CELLSR01CA186567 · NCI · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2013 to 2017
$3.6M
PHOTOACOUSTIC MICROSCOPY OF NEOVASCULARIZATION IN RENAL CANCER GROWTH AND THERAPYR01CA159959 · NCI · WASHINGTON UNIVERSITY · PI ARBEIT, JEFFREY MICHAEL · 2011 to 2015
$2.9M
NCI NIH HHS R01 CA159959NCI NIH HHS R01 CA186567
6 · The paper itself

Abstract

We applied high-speed photoacoustic microscopy (PAM) for both cortical microenvironment studies and dynamic brain studies, with micrometer-level optical resolution and a millisecond-level cross-sectional imaging speed over a millimeter-level field of view. We monitored blood flow redistribution in mini-stroke mouse models and cerebral autoregulation induced by a vasoactive agent. Our results collectively suggest that high-speed PAM is a promising tool for understanding dynamic neurophysiological phenomena, complementing conventional imaging modalities.

Indexed as

MicroscopyPhotoacoustic TechniquesAnimalsBrainFemaleMiceSpectrum Analysisblood flow redistributioncerebral autoregulationcortical hemodynamicsMEMS scanning mirrormicrohemorrhagephotoacoustic microscopy

Identifiers

PMID28009098
PMCPMC5576888
OpenAlexW2561694945

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.