Trial reportScientific reports2016
The clinical characteristics of corticosteroid-resistant refractory Mycoplasma Pneumoniae pneumonia in children.
Trial report in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for refractoryFrontiers in pediatrics · 2025Pooled it
- Targeting PAI-1 with TM5441 Mitigates Chronic Social Stress-Induced Anxiety-Like Behavior and Stress-Induced Increases in Ethanol Intake and Preference.Neurochemical research · 2026Article
- East Asia as a sentinel: risk-stratified corticosteroid therapy for paediatric macrolide-resistantEuropean respiratory review : an official journal of the European Respiratory Society · 2026Review
- Enhancing the identification of malonylation sites using AlphaFold2 and ensemble learning.Molecular diversity · 2026Article
- Risk factors associated with plastic bronchitis in children with severeJournal of thoracic disease · 2026Article
- Comparison of Different Corticosteroid Regimens for RefractoryInfection and drug resistance · 2026Article
- Lung ultrasound radiomics for identifying severeFrontiers in pediatrics · 2026Article
- Pulmonary lesion volume ratio and laboratory parameters as risk factors for plastic bronchitis in pediatric refractory Mycoplasma pneumoniae pneumonia.BMC pediatrics · 2025Article
- A Case of Refractory Mycoplasma Pneumonia With Extra-pulmonary Manifestations in a Community-Acquired Setting.Cureus · 2025Article
- Prediction model for severe mycoplasma pneumoniae pneumonia and analysis of macrolide-resistance in children: a case-control study.Italian journal of pediatrics · 2025Article
- Mitigation of depleted uranium-induced mitochondrial damage by ethylmalonic encephalopathy 1 protein via modulation of hydrogen sulfide and glutathione pathways.Archives of toxicology · 2025Article
- Challenges in the treatment of pediatric Mycoplasma pneumoniae pneumonia.European journal of pediatrics · 2024Review
- Elucidation of population stratifying markers and selective sweeps in crossbred Landlly pig population using genome-wide SNP data.Mammalian genome : official journal of the International Mammalian Genome Society · 2024Article
- Clinical features and "early" corticosteroid treatment outcome of pediatricFrontiers in cellular and infection microbiology · 2023Article
- Clinical analysis of hospital acquired mycoplasma pneumoniae infection after cardiac surgery: a case series.Journal of thoracic disease · 2022Article
- Development and validation of a nomogram to predict plastic bronchitis in children with refractory Mycoplasma pneumoniae pneumonia.BMC pulmonary medicine · 2022Article
- RefractoryJournal of clinical medicine · 2022Review
- Investigation of the relationship between community-acquired respiratory distress syndrome toxin and the high-mobility group box protein 1-toll-like receptors-myeloid differentiation factor 88 signaling pathway in Mycoplasma pneumoniae pneumonia.Italian journal of pediatrics · 2022Article
- Clinical Characteristics of Macrolide-RefractoryJournal of clinical medicine · 2022Article
- A Lung Ultrasound-Based Nomogram for the Prediction of RefractoryInfection and drug resistance · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To analyze the clinical characteristics of corticosteroid-resistant refractory Mycoplasma pneumoniae pneumonia (RMPP) and explore the related factors that predict corticosteroid-resistant RMPP. Retrospective analysis of 183 children with RMPP in our hospital admitted between January 1, 2012, and December 31, 2014 was performed. Of the 183 RMPP cases, 36 (19.7%) were corticosteroid-resistant RMPP cases. Corticosteroid-resistant RMPP cases had a longer duration of fever and hospitalization compared with corticosteroid-sensitive RMPP cases (P < 0.05). The radiographic findings of 123 (83.7%) cases of corticosteroid-sensitive RMPP apparently resolved after one week of corticosteroid treatment compared with 4 (11.1%) corticosteroid-resistant RMPP cases that had apparently resolution (P < 0.01). Twenty-four (75%) corticosteroid-resistant RMPP patients who received bronchoscopy had mucus plug formation while none of the corticosteroid-sensitive RMPP patients had mucus plug formation (P < 0.05). Multiple logistic regression analysis showed that duration of fever ≥11 days, percentage of lymphocytes ≤32%, CRP ≥48.73 mg/L and LDH ≥ 545.7 U/L were significant predictors of corticosteroid-resistant RMPP. Patients with corticosteroid-resistant RMPP had more severe presentations and more serious radiological findings. Clinicians might use the parameters of duration of fever, CRP, LDH and proportion of lymphocytes to identify children at higher risk of corticosteroid-resistant RMPP.
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