ArticleScientific reports2016
Acoustic micro-tapping for non-contact 4D imaging of tissue elasticity.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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Who cites it
77 citing papers in PubMed.
- Optical coherence elastography for shear wave characterization under temporal undersampling.Biomedical optics express · 2026Article
- Multi-frequency asynchronous optical coherence elastography by direct demodulation.Biomedical optics express · 2026Article
- Asynchronous optical coherence elastography and directional phase gradient analysis.Journal of biomedical optics · 2025Article
- Reconstruction of tensile and shear elastic moduli in anisotropic nearly incompressible media using Rayleigh wave phase and group velocities.Journal of biomedical optics · 2025Article
- Ultra-fast line-field swept source scanning optical coherence elastography.Biomedical optics express · 2025Article
- Multiscale analysis of equatorial sclera anisotropy: Revealing discrepancies in fiber orientation and mechanical properties.Science advances · 2025Article
- Tissue stiffness mapping by light sheet elastography.Science advances · 2025Article
- Feasibility using a compact fiber optic Sagnac interferometer for non-contact soft tissue surface mechanical wave speed detection.Biomedical optics express · 2025Article
- Revealing regional variations in scleral shear modulus in a rabbit eye model using multi-directional ultrasound optical coherence elastography.Scientific reports · 2024Article
- In Vivo Optical Coherence Elastography Unveils Spatial Variation of Human Corneal Stiffness.IEEE transactions on bio-medical engineering · 2024Article
- Acute alcohol consumption modulates corneal biomechanical properties as revealed by optical coherence elastography.Journal of biomechanics · 2024Article
- Full-field noise-correlation elastography for in-plane mechanical anisotropy imaging.Biomedical optics express · 2024Article
- Possible depth-resolved reconstruction of shear moduli in the cornea following collagen crosslinking (CXL) with optical coherence tomography and elastography.Biomedical optics express · 2023Article
- Article
- Acoustic Micro-Tapping Optical Coherence Elastography to Quantify Corneal Collagen Cross-Linking: An Ex Vivo Human Study.Ophthalmology science · 2023Article
- Noncontact Acoustic Micro-Tapping Optical Coherence Elastography for Quantification of Corneal Anisotropic Elasticity: In Vivo Rabbit Study.Translational vision science & technology · 2023Article
- Non-contact detection of ultrasound with light - Review of recent progress.Photoacoustics · 2023Review
- Article
- Recent advances in optical elastography and emerging opportunities in the basic sciences and translational medicine [Invited].Biomedical optics express · 2023Review
- Multiple Optical Elastography Techniques Reveal the Regulation of Corneal Stiffness by Collagen XII.Investigative ophthalmology & visual science · 2022Article
17 more citing papers are in PubMed but not listed here.
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9 authors.
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Abstract
Elastography plays a key role in characterizing soft media such as biological tissue. Although this technology has found widespread use in both clinical diagnostics and basic science research, nearly all methods require direct physical contact with the object of interest and can even be invasive. For a number of applications, such as diagnostic measurements on the anterior segment of the eye, physical contact is not desired and may even be prohibited. Here we present a fundamentally new approach to dynamic elastography using non-contact mechanical stimulation of soft media with precise spatial and temporal shaping. We call it acoustic micro-tapping (AμT) because it employs focused, air-coupled ultrasound to induce significant mechanical displacement at the boundary of a soft material using reflection-based radiation force. Combining it with high-speed, four-dimensional (three space dimensions plus time) phase-sensitive optical coherence tomography creates a non-contact tool for high-resolution and quantitative dynamic elastography of soft tissue at near real-time imaging rates. The overall approach is demonstrated in ex-vivo porcine cornea.
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