ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Optimal thallium-201 dose in cadmium-zinc-telluride SPECT myocardial perfusion imaging.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Prognostic significance of non-perfusion parameters of cadmium-zinc-telluride single-photon emission computed tomography myocardial perfusion imaging for individuals with normal myocardial perfusion: a large-scale single-center retrospective cohort study.Annals of nuclear medicine · 2025Article
- Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Simulating dose reduction for myocardial perfusion SPECT using a Poisson resampling method.Nuclear medicine and molecular imaging · 2021Article
- Toxicity of Thallium at Low Doses: A Review.International journal of environmental research and public health · 2019Review
- Tl-201 dosing for CZT SPECT: More new information.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Comparison of conventional and cadmium-zinc-telluride single-photon emission computed tomography for analysis of thallium-201 myocardial perfusion imaging: an exploratory study in normal databases for different ethnicities.The international journal of cardiovascular imaging · 2017Article
- Accuracy of washout rate analysis for thallium-201 single-photon emission computed tomography myocardial perfusion imaging using cadmium zinc telluride detectors: A phantom study.JRSM cardiovascular diseaseArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to determine the optimal thallium 201 chloride (thallium-201) dose using a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors (D-SPECT). METHODS AND
resultsThe optimal thallium-201 dose for obtaining left ventricular (LV) myocardial counts was determined from a phantom study. Consecutive 292 patients underwent stress myocardial perfusion imaging with a thallium-201 injection. Stress test comprised exercise or pharmacological (adenosine) provocation. We calculated an optimal thallium-201 dose that resulted in better LV myocardial counts during 6 minutes of acquisition time. We corrected the respective values according to the patient's age, sex, body mass index (BMI), and type of stress test. The lowest thallium-201 dose for obtaining acceptable imaging was 1.2 million counts. Radiopharmaceutical doses showed a positive correlation with the patient's age (P < .001), sex (P = .012), BMI (P < .001), and type of stress test (P < .001). Multivariate analysis revealed that the patient's BMI and the type of stress test were statistically significant factors for determining the correct radiopharmaceutical dose (P < .001 for both).
conclusionsFor clinical use of the CZT SPECT system, the optimal individual thallium-201 doses can be determined based on the patient's BMI and type of stress test.
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