ArticleInternational journal of reproductive biomedicine2016
Correlation of CA-125 serum level and clinico-pathological characteristic of patients with endometriosis.
Article in International journal of reproductive biomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Acupuncture monotherapy for endometriosis-related pain: A systematic review and meta-analysis.Medicine · 2025Pooled it
- Expression ofInternational journal of molecular sciences · 2023Pooled it
- Distinct and Convergent Roles of the Synovial Sarcoma X Breakpoint Family of Cancer-Testis Antigens in Ovarian Cancer.International journal of molecular sciences · 2026Article
- Serum biomarkers associated with disease stage and pain severity among women with endometriosis in Indonesia.Narra J · 2026Article
- Diagnosis of Endometriosis: Dual-Amplification Strategy Driven by Copper Nanoclusters.Analytical chemistry · 2026Article
- Article
- Relationship between serum CA125, prolactin and cortisol levels with disease stage and pain level in endometriosis patients.Narra J · 2026Article
- Immune-nutritional interactions in endometriosis: current evidence and future perspectives in disease management.Frontiers in immunology · 2026Review
- From Inflammation to Malignancy: The Link Between Endometriosis and Gynecological Cancers.International journal of molecular sciences · 2025Review
- Article
- In Search of Ideal Solutions for Cancer Diagnosis: From Conventional Methods to Protein Biomarkers in Liquid Biopsy.Proteomes · 2025Review
- Endometriosis: An Immunologist's Perspective.International journal of molecular sciences · 2025Review
- The Multifactorial Pathogenesis of Endometriosis: A Narrative Review Integrating Hormonal, Immune, and Microbiome Aspects.Medicina (Kaunas, Lithuania) · 2025Review
- Evaluating CA-125 and PET/CT for cancer detection in idiopathic inflammatory myopathies.Rheumatology (Oxford, England) · 2025Article
- Rectus Abdominis Muscle Endometriosis: A Unique Case Report with a Literature Review.Current issues in molecular biology · 2025Article
- A brief review of Lynch syndrome: understanding the dual cancer risk between endometrial and colorectal cancer.Oncology reviews · 2025Review
- Case Report: Serous borderline ovarian tumor and extensive abdominopelvic endometriosis mimicking advanced epithelial ovarian cancer in a postmenopausal patient.Frontiers in medicine · 2025Article
- Non-Surgical Options for The Diagnosis of Endometriosis in Low-Resource Settings: A Comparative Study.International journal of women's health · 2025Article
- Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence.npj women's health · 2025Review
- Endometriosis: Future Biological Perspectives for Diagnosis and Treatment.International journal of molecular sciences · 2024Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer antigen 125 (CA-125) is a glycoprotein biomarker that is used in women with pelvic masses such as endometriosis and maybe is useful in practice of patients suspicious to endometriosis.
objectiveThe aim of this study was to evaluate the association between preoperative serum CA-125 levels and clinic pathological characteristic in women with endometriosis, and find out the best serum CA-125 levels cut-off in pre and post menopause women. MATERIALS AND
methodsSerum CA-125 levels in 87 women aged 21-54 years suspected to endometriosis with pelvic pain, dysmenorrhea, or dyspareunia were measured preoperatively. Also the association between clinic pathological characteristic and serum CA-125 level were analyzed.
resultsThe mean age of women was 32.22±6.91. The mean serum CA-125 level was 49.93±4.30 U/mL. There was a significant correlation between the endometriosis stage, lesion size, adhesion score and preoperative CA-125 plasma concentration. However, we did not found significant differences in age, marital status, patient's complaints, and pelvic pain associated to Ca125 serum level. The suggested preoperative serum cut-off levels in premenopausal and postmenopausal patients were 37 U/ml and 35 U/ml, respectively.
conclusionAccording to the results, preoperative serum CA-125 is an important predictor for patients with endometriosis and it should be taken into consideration when surgical management is suspected, especially if stage of disease, lesion size and adhesion score are undertaken.
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28008424PMC5153578What OpenQuestion holds
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