ArticleNeuropsychiatric disease and treatment2016
Incidence, risk factors, and phenomenological characteristics of postoperative delirium in patients receiving intravenous patient-controlled analgesia: a prospective cohort study.
Article in Neuropsychiatric disease and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Assessment and report of individual symptoms in studies of delirium in postoperative populations: a systematic review.Age and ageing · 2024Pooled it
- Understanding the association between pain and delirium in older hospital inpatients: systematic review and meta-analysis.Age and ageing · 2024Pooled it
- The effect of early postoperative acute pain on postoperative delirium in older persons undergoing abdominal surgery: a secondary analysis of multicenter prospective data.European geriatric medicine · 2026Article
- Patient satisfaction with postoperative analgesia after hepatobiliary and pancreatic surgery: a retrospective analysis.Frontiers in surgery · 2026Article
- Nurses' knowledge and attitudes toward patient-controlled analgesia for postoperative pain control in a tertiary hospital in South Korea.BMC nursing · 2022Article
- In Reference to Effects of Preoperative Anxiety on Postoperative Delirium in Elderly Patients [Letter].Clinical interventions in aging · 2021Article
- Exosome α-Synuclein Release in Plasma May be Associated With Postoperative Delirium in Hip Fracture Patients.Frontiers in aging neuroscience · 2020Article
- Preoperational chronic pain impairs the attention ability before surgery and recovery of attention and memory abilities after surgery in non-elderly patients.Journal of pain research · 2019Article
- An innovative nonpharmacological intervention combined with intravenous patient-controlled analgesia increased patient global improvement in pain and satisfaction after major surgery.Neuropsychiatric disease and treatment · 2017Article
- Delirium Risk of Dexmedetomidine and Midazolam in Patients Treated with Postoperative Mechanical Ventilation: a Meta-analysis.Open medicine (Warsaw, Poland) · 2017Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntravenous patient-controlled analgesia (IVPCA) is a common method of relieving pain which is a risk factor of postoperative delirium (POD). However, research concerning POD in IVPCA patients is limited.
objectiveWe aimed to determine the incidence, risk factors, and phenomenological characteristics of POD in patients receiving IVPCA.
methodsA prospective, cohort study was conducted in post-general anesthesia IVPCA patients aged ≥60 years. POD was measured by the Nursing Delirium Screening Scale (NuDESC; 0-10). Delirium, pain severity at rest and/or on movement, and side effects of IVPCA during 3 postoperative days were examined twice-daily by the acute pain service team. Pain severity is measured by an 11-point verbal numerical rating scale (11-point VNRS) (0-10). An 11-point VNRS >3 was considered inadequate pain relief. If POD (detected by NuDESC ≥1) is suspected, consulting a neurologist or a psychiatrist to confirm suspected POD is required.
resultsIn total, 1,608 patients were included. The incidence rate of POD was 2.2%. Age ≥70 years and American Society of Anesthesiologists physical status >III were the risk factors of POD in IVPCA patients. Approximately three-quarters of all POD cases occurred within the first 2 postoperative days. For pain at rest, patients with inadequate pain relief had significantly greater rates of POD than patients with adequate pain relief (day 1, 8.4% vs 1.5%,
conclusionThe incidence rate of POD in IVPCA patients was low. Further research is warranted concerning POD and IVPCA pain management.
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