Evidence map›Paper›PMID 28008256›Full record

ArticleNeuropsychiatric disease and treatment2016

Blonanserin treatment in patients with methamphetamine-induced psychosis comorbid with intellectual disabilities.

Kosuke Okazaki, Manabu Makinodan, Kazuhiko Yamamuro, Tomoyo Takata, Toshifumi Kishimoto

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kosuke OkazakiDepartment of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan.
Manabu MakinodanDepartment of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan.
Kazuhiko YamamuroDepartment of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan.
Tomoyo TakataDepartment of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan.
Toshifumi KishimotoDepartment of Psychiatry, Nara Medical University School of Medicine, Kashihara, Japan.
Nara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMethamphetamine (MA) use has recently been associated with high levels of psychiatric hospitalization and serious social dysfunction. MA use causes frequent psychotic symptoms, which can be treated with antipsychotics. However, people with intellectual disabilities (ID) are vulnerable to adverse effects resulting from treatment with antipsychotic medications.

methodWe report two cases of MA-induced psychosis (MAP) in patients with ID who were treated with the antipsychotic blonanserin.

resultsIn both the cases presented, symptoms of psychosis were improved by switching medications from other antipsychotic drugs to blonanserin. Despite the presence of ID in these patients, no significant adverse effects, such as sedation, were detected after treatment with blonanserin.

conclusionBlonanserin may be an effective and well-tolerated pharmacotherapeutical treatment for patients with MAP comorbid with ID. However, further work is necessary to validate this claim.

Indexed as

blonanserinintellectual disabilitiesmethamphetaminemethamphetamine-induced psychosis

Identifiers

PMID28008256
PMCPMC5167479
OpenAlexW2561019791

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.