Evidence map›Paper›PMID 28008210›Full record

ArticleJournal of the American Statistical Association2016

Identification and Estimation of Causal Mechanisms in Clustered Encouragement Designs: Disentangling Bed Nets using Bayesian Principal Stratification.

Laura Forastiere, Fabrizia Mealli, Tyler J VanderWeele

Abstract read
In one paragraph

Article in Journal of the American Statistical Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. An overview of propensity score matching methods for clustered data.Statistical methods in medical research · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. A Tutorial in Bayesian Potential Outcomes Mediation Analysis.Structural equation modeling : a multidisciplinary journal · 2018
    Article
  11. Estimating peer effects in networks with peer encouragement designs.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura ForastiereUniversity of Florence.
Fabrizia MealliUniversity of Florence.
Tyler J VanderWeeleHarvard School of Public Health.

Funding

Identification and Inference for Longitudinal Causal Mediation Analysis in HIVR01AI104459 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI SHPITSER, ILYA, VANDERWEELE, TYLER · 2013 to 2017
$2.0M
Theory and methods for sufficient cause interactionsR01ES017876 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI VANDERWEELE, TYLER · 2010 to 2014
$1.2M
NIAID NIH HHS R01 AI104459NIEHS NIH HHS R01 ES017876
6 · The paper itself

Abstract

Exploration of causal mechanisms is often important for researchers and policymakers to understand how an intervention works and how it can be improved. This task can be crucial in clustered encouragement designs (CED). Encouragement design studies arise frequently when the treatment cannot be enforced because of ethical or practical constrains and an encouragement intervention (information campaigns, incentives, etc) is conceived with the purpose of increasing the uptake of the treatment of interest. By design, encouragements always entail the complication of non-compliance. Encouragements can also give rise to a variety of mechanisms, particularly when encouragement is assigned at cluster level. Social interactions among units within the same cluster can result in spillover effects. Disentangling the effect of encouragement through spillover effects from that through the enhancement of the treatment would give better insight into the intervention and it could be compelling for planning the scaling-up phase of the program. Building on previous works on CEDs and non-compliance, we use the principal stratification framework to define stratum-specific causal effects, that is, effects for specific latent subpopulations, defined by the joint potential compliance statuses under both encouragement conditions. We show how the latter stratum-specific causal effects are related to the decomposition commonly used in the literature and provide flexible homogeneity assumptions under which an extrapolation across principal strata allows one to disentangle the effects. Estimation of causal estimands can be performed with Bayesian inferential methods using hierarchical models to account for clustering. We illustrate the proposed methodology by analyzing a cluster randomized experiment implemented in Zambia and designed to evaluate the impact on malaria prevalence of an agricultural loan program intended to increase the bed net coverage. Farmer households assigned to the program could take advantage of a deferred payment and a discount in the purchase of new bed nets. Our analysis shows a lack of evidence of an effect of the offering of the program to a cluster of households through spillover effects, that is through a greater bed net coverage in the neighborhood.

Identifiers

PMID28008210
PMCPMC5166715

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.