Evidence map›Paper›PMID 28007782›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Serum stearic acid/palmitic acid ratio as a potential predictor of diabetes remission after Roux-en-Y gastric bypass in obesity.

Linjing Zhao, Yan Ni, Haoyong Yu, Pin Zhang, Aihua Zhao, Yuqian Bao, Jiajian Liu, Tianlu Chen, Guoxiang Xie, Jun Panee and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Metabolomic signatures after bariatric surgery - a systematic review.Reviews in endocrine & metabolic disorders · 2022
    Pooled it
  2. Trial
  3. Dysreflexic dilemma: do we need a revised definition for autonomic dysreflexia?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Article
  4. Article
  5. Saudi journal of biological sciences · 2023
    Review
  6. Article
  7. Article
  8. Review
  9. Metabolic surgery in China: present and future.Journal of molecular cell biology · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  14. Circulating and tissue biomarkers as predictors of bromine gas inhalation.Annals of the New York Academy of Sciences · 2020
    Article
  15. Fecal metagenomics and metabolomics reveal gut microbial changes after bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2020
    Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Linjing ZhaoShanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Yan NiShanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Haoyong YuDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Pin ZhangDepartment of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China; and.
Aihua ZhaoShanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Yuqian BaoShanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Jiajian LiuShanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Tianlu ChenShanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Guoxiang XieUniversity of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Jun PaneeDepartment of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Manoa, Hawaii, USA.
Wenlian ChenUniversity of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Cynthia RajaniUniversity of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Runmin WeiUniversity of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Mingming SuUniversity of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Weiping JiaShanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China; wpjia@sjtu.edu.cn.
Wei JiaShanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China; wjia@cc.hawaii.edu.
Shanghai Sixth People's Hospital · CNCancer Center of Hawaii · USShanghai Jiao Tong University · CNUniversity of Hawaii Cancer CenterUniversity of Hawaiʻi at Mānoa · US

Funding

RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MOKUAU, NOREEN, SHIRAMIZU, BRUCE T · 2012 to 2018
$21.1M
NIMHD NIH HHS U54 MD007584
6 · The paper itself

Abstract

Endogenous fatty acid metabolism that results in elongation and desaturation lipid products is thought to play a role in the development of type 2 diabetes mellitus (T2DM). In this study, we evaluated the potential of estimated elongase and desaturase activities for use as predictive markers for T2DM remission after Roux-en-Y gastric bypass (RYGB). The results of a targeted metabolomics approach from 2 independent studies were used to calculate 24 serum FA concentration ratios (product/precursor). Gene expression data from an open public data set was also analyzed. In a longitudinal study of 38 obese diabetic patients with RYGB, we found higher baseline stearic acid/palmitic acid (S/P) ratio. This ratio reflects an

Indexed as

Gastric BypassAcetyltransferasesAdultAgedBiomarkersDiabetes MellitusFatty Acid ElongasesFemaleHumansMaleMiddle AgedObesityPalmitic AcidStearic AcidsAcetyltransferasesBiomarkersELOVL6 protein, humanFatty Acid ElongasesPalmitic Acidstearic acidStearic Acidsbariatric surgeryelovl6fatty acid metabolismtargeted metabolomicsUPLC/QTOFMS

Identifiers

PMID28007782
PMCPMC6159710
OpenAlexW2564264270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.