Evidence map›Paper›PMID 28007777›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Noninvasive Measurement of mTORC1 Signaling with

Charles Truillet, John T Cunningham, Matthew F L Parker, Loc T Huynh, Crystal S Conn, Davide Ruggero, Jason S Lewis, Michael J Evans

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. A PET Imaging Strategy for Interrogating Target Engagement and Oncogene Status in Pancreatic Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
  9. Article
  10. Article
  11. Quantitative imaging of receptor-ligand engagement in intact live animals.Journal of controlled release : official journal of the Controlled Release Society · 2018
    Article
  12. NoninvasiveJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Charles TruilletDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.
John T CunninghamDepartment of Urology, University of California San Francisco, San Francisco, California.
Matthew F L ParkerDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.
Loc T HuynhDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.
Crystal S ConnDepartment of Urology, University of California San Francisco, San Francisco, California.
Davide RuggeroDepartment of Urology, University of California San Francisco, San Francisco, California.
Jason S LewisDepartment of Radiology and the Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York. michael.evans@ucsf.edu lewisj2@mskcc.org.
Michael J EvansDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California. michael.evans@ucsf.edu lewisj2@mskcc.org.
University of California, San Francisco · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Translational InformaticsP30CA082103 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer Leigh Clarke · 1999 to 2026
$209.7M
Annotating Oncogene Status in Prostate Cancer with Zr-89-transferrin PETR01CA176671 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI EVANS, MICHAEL JOHN, LEWIS, JASON S. · 2013 to 2017
$3.1M
Biomarkers for predicting response to Hsp90 therapyR01CA172546 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CHIOSIS, GABRIELA, DUNPHY, MARK P. · 2013 to 2017
$2.9M
Pharmcogenomic dissection of mTOR translational targets in prostate cancerR01CA154916 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUGGERO, DAVIDE · 2011 to 2018
$2.8M
Noninvasive measurement of oncogenic signaling pathways with 89Zr-transferrinR00CA172695 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EVANS, MICHAEL JOHN · 2014 to 2016
$728k
Noninvasive measurement of oncogenic signaling pathways with 89Zr-transferrinK99CA172695 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI EVANS, MICHAEL JOHN · 2013 to 2013
$91k
NCI NIH HHS K99 CA172695NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA082103NCI NIH HHS R00 CA172695NCI NIH HHS R01 CA154916NCI NIH HHS R01 CA172546NCI NIH HHS R01 CA176671
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorHumansMechanistic Target of Rapamycin Complex 1MiceMolecular ImagingPositron-Emission TomographyRadiopharmaceuticalsTOR Serine-Threonine KinasesTransferrinXenograft Model Antitumor AssaysZirconiumMechanistic Target of Rapamycin Complex 1MTOR protein, humanRadiopharmaceuticalsTOR Serine-Threonine KinasesTransferrinZirconium

Identifiers

PMID28007777
PMCPMC5474159
OpenAlexW2562486086

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.