Evidence map›Paper›PMID 28007768›Full record

ArticleAJNR. American journal of neuroradiology2017

Toward Precision and Reproducibility of Diffusion Tensor Imaging: A Multicenter Diffusion Phantom and Traveling Volunteer Study.

E M Palacios, A J Martin, M A Boss, F Ezekiel, Y S Chang, E L Yuh, M J Vassar, D M Schnyer, C L MacDonald, K L Crawford and 4 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.

  1. Pooled it
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  10. Axonal injury, sleep disturbances, and memory following traumatic brain injury.Annals of clinical and translational neurology · 2024
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

E M PalaciosFrom the Departments of Radiology and Biomedical Imaging (E.M.P., A.J.M., F.E., Y.S.C., E.L.Y., P.M.).ORCID 0000-0001-8849-6140
A J MartinFrom the Departments of Radiology and Biomedical Imaging (E.M.P., A.J.M., F.E., Y.S.C., E.L.Y., P.M.).ORCID 0000-0002-7963-4000
M A BossNational Institute of Standards and Technology (M.A.B.), Boulder, Colorado.ORCID 0000-0002-9492-767X
F EzekielFrom the Departments of Radiology and Biomedical Imaging (E.M.P., A.J.M., F.E., Y.S.C., E.L.Y., P.M.).ORCID 0000-0003-4622-3755
Y S ChangFrom the Departments of Radiology and Biomedical Imaging (E.M.P., A.J.M., F.E., Y.S.C., E.L.Y., P.M.).ORCID 0000-0002-9539-4553
E L YuhFrom the Departments of Radiology and Biomedical Imaging (E.M.P., A.J.M., F.E., Y.S.C., E.L.Y., P.M.).ORCID 0000-0002-1180-2274
M J VassarNeurological Surgery and Brain and Spinal Injury Center (M.J.V.).ORCID 0000-0001-6748-6939
D M SchnyerDepartment of Psychology (D.M.S.), University of Texas, Austin, Texas.ORCID 0000-0002-7472-2853
C L MacDonaldDepartment of Neurological Surgery (C.L.M.), University of Washington, Seattle, Washington.ORCID 0000-0002-7419-996X
K L CrawfordMark and Mary Stevens Neuroimaging and Informatics Institute (K.L.C., A.I., A.W.T.), University of Southern California, Los Angeles, California.ORCID 0000-0002-3294-0828
A IrimiaMark and Mary Stevens Neuroimaging and Informatics Institute (K.L.C., A.I., A.W.T.), University of Southern California, Los Angeles, California.ORCID 0000-0002-9254-9388
A W TogaMark and Mary Stevens Neuroimaging and Informatics Institute (K.L.C., A.I., A.W.T.), University of Southern California, Los Angeles, California.ORCID 0000-0003-1454-8643
P MukherjeeFrom the Departments of Radiology and Biomedical Imaging (E.M.P., A.J.M., F.E., Y.S.C., E.L.Y., P.M.) pratik.mukherjee@ucsf.edu.ORCID 0000-0001-7473-7409
TRACK-TBI Investigators
Laboratoire d’Imagerie Biomédicale · FRSan Francisco General Hospital · USUniversity of Southern California · USNational Institute of Standards and Technology · USThe University of Texas at Austin · USUniversity of Washington · US

Funding

Transforming Research and Clinical Knowledge in Traumatic Brain InjuryU01NS086090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIAZ-ARRASTIA, RAMON, GIACINO, JOSEPH THOMAS · 2013 to 2017
$19.1M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
Endovascular Magnetic Catheter for Interventional MRIR01EB012031 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM, MARTIN, ALASTAIR J · 2011 to 2021
$4.8M
Towards Baby Brain Connectome: a Study of Newborn Brain NetworksR01HD072074 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HESS, CHRISTOPHER PAUL, XU, DUAN · 2013 to 2017
$3.0M
Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce ToxicityR01CA194533 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM · 2015 to 2019
$2.6M
Social Networks and Well-being in Late Life: A Study of Daily MechanismsR01AG046460 · NIA · UNIVERSITY OF TEXAS AT AUSTIN · PI FINGERMAN, KAREN L · 2015 to 2019
$2.5M
Genetic Influences on Human Neuroanatomical ShapesR01MH094343 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOGA, ARTHUR W · 2012 to 2016
$2.4M
Macrostructural and Microstructural Imaging Biomarkers of Traumatic Brain InjuryR01NS060776 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MUKHERJEE, PRATIK · 2009 to 2012
$1.8M
MRI Corticography (MRCoG): Micro-scale Human Cortical ImagingR24MH106096 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI FEINBERG, DAVID ALAN, LIU, CHUNLEI · 2014 to 2016
$1.4M
Multimodality Image-Based Assessment System for Traumatic Brain InjuryR44NS081792 · NINDS · KITWARE, INC. · PI AYLWARD, STEPHEN R, NIETHAMMER, MARC · 2015 to 2016
$1.3M
A Phase I Study of CED of Liposomal-Irinotecan using imaging in High Grade GliomaR21CA186140 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUTOWSKI, NICHOLAS A · 2014 to 2015
$651k
POLIO DISABILITIES: PERSONAL MEANING, WELL-BEING AND AGER01HD031526 · NICHD · MADLYN/LEONARD ABRAMSON CTR/JEWISH LIFE · PI LUBORSKY, MARK R · 1993 to 1997
–
NCI NIH HHS R01 CA194533NCI NIH HHS R21 CA186140NIA NIH HHS R01 AG046460NIBIB NIH HHS P41 EB015922NIBIB NIH HHS R01 EB012031NICHD NIH HHS R01 HD031526NICHD NIH HHS R01 HD072074NIMH NIH HHS R01 MH094343NIMH NIH HHS R24 MH106096NINDS NIH HHS R01 NS060776NINDS NIH HHS R44 NS081792NINDS NIH HHS U01 NS086090
6 · The paper itself

Abstract

background and purposePrecision medicine is an approach to disease diagnosis, treatment, and prevention that relies on quantitative biomarkers that minimize the variability of individual patient measurements. The aim of this study was to assess the intersite variability after harmonization of a high-angular-resolution 3T diffusion tensor imaging protocol across 13 scanners at the 11 academic medical centers participating in the Transforming Research and Clinical Knowledge in Traumatic Brain Injury multisite study. MATERIALS AND

methodsDiffusion MR imaging was acquired from a novel isotropic diffusion phantom developed at the National Institute of Standards and Technology and from the brain of a traveling volunteer on thirteen 3T MR imaging scanners representing 3 major vendors (GE Healthcare, Philips Healthcare, and Siemens). Means of the DTI parameters and their coefficients of variation across scanners were calculated for each DTI metric and white matter tract.

resultsFor the National Institute of Standards and Technology diffusion phantom, the coefficients of variation of the apparent diffusion coefficient across the 13 scanners was <3.8% for a range of diffusivities from 0.4 to 1.1 × 10

conclusionsThe results suggest the feasibility of standardizing DTI across 3T scanners from different MR imaging vendors in a large-scale neuroimaging research study.

Indexed as

BrainDiffusion Tensor ImagingHumansNeuroimagingPhantoms, ImagingReproducibility of ResultsVolunteers

Identifiers

PMID28007768
PMCPMC5352533
OpenAlexW2567143195

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.