Gradients of Connectivity in the Cerebral Cortex.

Fenna M Krienen, Chet C Sherwood

Abstract readComment

In one paragraph

Article in Trends in cognitive sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Cortical gradient compression links cognition and transcriptomic signatures in primary angle-closure glaucoma.Communications biology · 2026
Article
Brain connectome gradient dysfunction in patients with end-stage renal disease and its association with clinical phenotype and cognitive deficits.Communications biology · 2025
Article
Brain structure-function coupling associated with cognitive impairment in cerebral small vessel disease.Frontiers in neuroscience · 2023
Review
Heritability of hippocampal functional and microstructural organisation.NeuroImage · 2022
Article
The impact of ischemic stroke on connectivity gradients.NeuroImage. Clinical · 2019
Article

4 · The record

Corrections and comments

Comment on
Situating the default-mode network along a principal gradient of macroscale cortical organization.2016

5 · Who and what money

Authors and funding

2 authors.

Fenna M KrienenDepartment of Genetics, Harvard Medical School, Boston, MA, USA; Broad Institute, Cambridge, MA, USA. Electronic address: fenna_krienen@hms.harvard.edu.

Chet C SherwoodDepartment of Anthropology, Center for the Advanced Study of Human Paleobiology and GW Mind-Brain Institute, The George Washington University, Washington, DC, USA. Electronic address: sherwood@gwu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human neocortex is organized with distributed networks that connect distant regions together, but what determines their spatial layout? A recent study sheds light on the topological placement of regions along the cortical surface in relation to gradients of connectivity in both humans and macaques.

Indexed as

Cerebral CortexConnectomeHumansMagnetic Resonance ImagingNeocortexNerve Netassociation cortexCoCoMacconnectivitycortical networksdefault networkHuman Connectome Project

Identifiers

PMID28007482

DOI10.1016/j.tics.2016.12.002

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.