Evidence map›Paper›PMID 28007229›Full record

ReviewAmerican journal of obstetrics and gynecology2017

Sexually transmitted diseases and infertility.

Danielle G Tsevat, Harold C Wiesenfeld, Caitlin Parks, Jeffrey F Peipert

Open access · greenAbstract readReview
In one paragraph

Review in American journal of obstetrics and gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 7 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 7 syntheses or guidelines pooled it, 429 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Global epidemiology ofSexually transmitted infections · 2021
    Pooled it
  5. Pooled it
  6. Psychological aspects of infertility. A systematic review.The Journal of international medical research · 2020
    Pooled it
  7. Pooled it
  8. Trial
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  12. The role of extracellular DNA inJournal of bacteriology · 2026
    Review
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124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Danielle G TsevatDivision of Clinical Research, Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, St Louis, MO.
Harold C WiesenfeldDivision of Gynecologic Specialties, Department of Obstetrics and Gynecology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Caitlin ParksDivision of Clinical Research, Department of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, St Louis, MO.
Jeffrey F PeipertDepartment of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN. Electronic address: jpeipert@iu.edu.
Washington University in St. Louis · USIndiana University Health · USUniversity of Pittsburgh · US

Funding

Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
NCATS NIH HHS KL2 TR000450
6 · The paper itself

Abstract

Female infertility, including tubal factor infertility, is a major public health concern worldwide. Most cases of tubal factor infertility are attributable to untreated sexually transmitted diseases that ascend along the reproductive tract and are capable of causing tubal inflammation, damage, and scarring. Evidence has consistently demonstrated the effects of Chlamydia trachomatis and Neisseria gonorrhoeae as pathogenic bacteria involved in reproductive tract morbidities including tubal factor infertility and pelvic inflammatory disease. There is limited evidence in the medical literature that other sexually transmitted organisms, including Mycoplasma genitalium, Trichomonas vaginalis, and other microorganisms within the vaginal microbiome, may be important factors involved in the pathology of infertility. Further investigation into the vaginal microbiome and other potential pathogens is necessary to identify preventable causes of tubal factor infertility. Improved clinical screening and prevention of ascending infection may provide a solution to the persistent burden of infertility.

Indexed as

Chlamydia InfectionsChlamydia trachomatisFemaleGonorrheaHumansInfertility, FemaleMycoplasma genitaliumMycoplasma InfectionsNeisseria gonorrhoeaePelvic Inflammatory DiseaseSexually Transmitted DiseasesTrichomonas vaginalisTrichomonas VaginitischlamydiagonorrheainfertilitySTDSTI

Identifiers

PMID28007229
PMCPMC5193130
OpenAlexW2560903427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.