Evidence map›Paper›PMID 28006854›Full record

ArticleMuscle & nerve2017

Quantification of human upper extremity nerves and fascicular anatomy.

Natalie A Brill, Dustin J Tyler

Open access · greenAbstract read
In one paragraph

Article in Muscle & nerve, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
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  15. Review
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  17. Bending Properties of Materials for Peripheral Nerve Interfaces.IEEE International Conference on Nano/Micro Engineered and Molecular Systems. IEEE International Conference on Nano/Micro Engineered and Molecular Systems · 2020
    Article
  18. Article
  19. Intraoperative Responses May Predict Chronic Performance of Composite Flat Interface Nerve Electrodes on Human Femoral Nerves.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Natalie A BrillDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44104, USA.
Dustin J TylerDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44104, USA.
Case Western Reserve University · USLouis Stokes Cleveland VA Medical Center · US

Funding

Primate model of an intracortically controlled FES prostR01NS053603 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KENNEDY, ANN KATHRYN, MILLER, LEE · 2006 to 2021
$7.1M
Integrated Neural Engineering and Rehabilitation Training ProgramT32EB004314 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI Jeffrey R Capadona, Robert F. Kirsch · 2004 to 2026
$6.1M
Peripheral Nerve Implementation of Functional NeuroprosthesesR21NS058705 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI TYLER, DUSTIN J. · 2007 to 2008
$372k
NIBIB NIH HHS T32 EB004314NINDS NIH HHS R01 NS053603NINDS NIH HHS R21 NS058705
6 · The paper itself

Abstract

introductionIn this study we provide detailed quantification of upper extremity nerve and fascicular anatomy. The purpose is to provide values and trends in neural features useful for clinical applications and neural interface device design.

methodsNerve cross-sections were taken from 4 ulnar, 4 median, and 3 radial nerves from 5 arms of 3 human cadavers. Quantified nerve features included cross-sectional area, minor diameter, and major diameter. Fascicular features analyzed included count, perimeter, area, and position.

resultsMean fascicular diameters were 0.57 ± 0.39, 0.6 ± 0.3, 0.5 ± 0.26 mm in the upper arm and 0.38 ± 0.18, 0.47 ± 0.18, 0.4 ± 0.27 mm in the forearm of ulnar, median, and radial nerves, respectively. Mean fascicular diameters were inversely proportional to fascicle count.

conclusionDetailed quantitative anatomy of upper extremity nerves is a resource for design of neural electrodes, guidance in extraneural procedures, and improved neurosurgical planning. Muscle Nerve 56: 463-471, 2017.

Indexed as

ArmCadaverFemaleHumansMaleMedian NervePeripheral NervesRadial NerveUlnar NerveUpper Extremityfasciclesintraneural topographynerve dimensionsnerve surgeryneural anatomyneuroprosthesisperipheral nerve

Identifiers

PMID28006854
PMCPMC5712902
OpenAlexW2560953689

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.