Evidence map›Paper›PMID 28006853›Full record

ArticleInternational journal of cancer2017

Survival predictors of Burkitt's lymphoma in children, adults and elderly in the United States during 2000-2013.

Fahad Mukhtar, Paolo Boffetta, Harvey A Risch, Jong Y Park, Omonigho M Bubu, Lindsay Womack, Thuan V Tran, Janice C Zgibor, Hung N Luu

Open access · bronzeAbstract read
In one paragraph

Article in International journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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  13. Bilateral jaws involvement of Burkitt's lymphoma in a pediatric patient.Journal of clinical and experimental dentistry · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Fahad MukhtarDepartment of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL.
Paolo BoffettaIcahn School of Medicine, Mount Sinai School of Medicine, Tisch Cancer Institute, New York, NY.
Harvey A RischDepartment of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, CT.
Jong Y ParkDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612.
Omonigho M BubuDepartment of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL.
Lindsay WomackDepartment of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL.
Thuan V TranVietnam National Cancer Hospital, Hanoi, Vietnam.
Janice C ZgiborDepartment of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL.
Hung N LuuDepartment of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL.
University of South Florida · USInstitute of Mathematics · VNMoffitt Cancer Center · USTisch Cancer InstituteVanderbilt University · USYale University · US

Funding

Regional Center of Research Excellence in Cancer and Other Non-Communicable Disease Epidemiology and Prevention in VietnamP20CA210300 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHU, XIAO-OU, TRAN, THUAN · 2016 to 2017
$549k
NCI NIH HHS P20 CA210300
6 · The paper itself

Abstract

Burkitt's Lymphoma (BL) has three peaks of occurrence, in children, adults and elderly, at 10, 40 and 70 years respectively. To the best of our knowledge, no study has been conducted to assess predictors of survival in the three age groups. We hypothesized that survival predictors may differ by age group. We, therefore, sought to determine survival predictors for BL in these three groups: children (<15 years of age), adults (40-70 years of age) and elderly (>70 years of age). Using the Surveillance, Epidemiology, and End Results (SEER) database covering the years 2000-2013, we identified 797 children, 1,994 adults and 757 elderly patients newly diagnosed with BL. We used adjusted Cox proportional hazards regression models to determine prognostic factors for survival for each age group. Five-year relative survival in BL for children, adults and elderly were 90.4, 47.8 and 28.9%, respectively. Having at least Stage II disease and multiple primaries were associated with higher mortality in the elderly group. In adults, multiple primaries, Stage III or IV disease, African American race and bone marrow primary were associated with increased mortality whereas Stage IV disease and multiple primaries were associated with worse outcome in children. These findings demonstrate commonalities and differences in predictors of survival that may have implications for management of BL patients.

Indexed as

AdolescentAdultAgedAge FactorsBurkitt LymphomaChildFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisNeoplasm StagingPrognosisProportional Hazards ModelsSEER ProgramBurkitt's LymphomaprognosisSEERsurvival

Identifiers

PMID28006853
PMCPMC6919213
OpenAlexW2567247892

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.