ArticlePloS one2016
Obstetrical Complications in Women with Endometriosis: A Cohort Study in Japan.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- The relationship between hypertensive disorders in pregnancy and endometriosis: a systematic review and meta-analysis.Reproductive health · 2024Pooled it
- Endometriosis increases the risk of gestational diabetes: a meta-analysis stratified by mode of conception, disease localization and severity.Scientific reports · 2023Pooled it
- Is there an Increased Risk for Unfavorable Obstetric Outcomes in Women with Endometriosis? An Evaluation of Evidences.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2020Pooled it
- Endometriosis and adverse maternal, fetal and neonatal outcomes, a systematic review and meta-analysis.Human reproduction (Oxford, England) · 2018Pooled it
- Obstetric Complications in Pregnant Women with and without Endometriosis: A Comparative Cohort Study.International journal of fertility & sterility · 2026Article
- Obstetric outcomes after IVF/ICSI treatment in women with endometriosis and/or adenomyosis diagnosed by ultrasonography: a prospective cohort study.Human reproduction (Oxford, England) · 2026Observational
- Pregnancy in women with advanced endometriosis and adenomyosis: possible complications and the role of surgery.Reproductive biology and endocrinology : RB&E · 2025Review
- Endometriosis and associations with risks of adverse pregnancy and perinatal outcomes: a case-control study in Egypt.BMC pregnancy and childbirth · 2025Article
- Causal Effects of Endometriosis Stages on Adverse Pregnancy and Perinatal Outcomes: A Mendelian Randomization Study.International journal of women's health · 2025Article
- Association between endometriosis and perinatal complications: a case-control study.BMC pregnancy and childbirth · 2024Article
- Endometriosis and adverse pregnancy outcomes: A case-control study.International journal of reproductive biomedicine · 2024Article
- A Lifelong Impact on Endometriosis: Pathophysiology and Pharmacological Treatment.International journal of molecular sciences · 2023Review
- Pregnancy outcomes in women with endometriosis and/or ART use: a population-based cohort study.Human reproduction (Oxford, England) · 2022Article
- Endometriosis: A Disease with Few Direct Treatment Options.Molecules (Basel, Switzerland) · 2022Review
- Endometriosis and preterm birth: A Danish cohort study.Acta obstetricia et gynecologica Scandinavica · 2022Article
- Association between Endometriosis and Delivery Outcomes: A Systematic Review and Meta-Analysis.Biomedicines · 2022Review
- Association of preconception dysmenorrhea with obstetric complications: the Japan Environment and Children's Study.BMC pregnancy and childbirth · 2022Article
- Placenta Accreta Spectrum Disorder Complicated with Endometriosis: Systematic Review and Meta-Analysis.Biomedicines · 2022Review
- Placenta Previa Complicated with Endometriosis: Contemporary Clinical Management, Molecular Mechanisms, and Future Research Opportunities.Biomedicines · 2021Review
- Therapeutic Potential of Date Palm against Human Infertility: A Review.Metabolites · 2021Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndometriosis, which occurs in approximately 10% of women of reproductive age, is defined as the presence of endometrial tissue outside the uterus. Women with endometriosis are more likely to have difficulty conceiving and tend to receive infertility treatment, including assisted reproductive technology (ART) therapy. There has not yet been a prospective cohort study examining the effects of endometriosis on pregnancy outcome in pregnant Japanese women. METHODOLOGY: This was a prospective cohort study of the incidence of obstetrical complications in women with endometriosis using data of the Japan Environment & Children's Study (JECS). Included in this study were 9,186 pregnant women in the JECS with or without a history of endometriosis who gave birth or stillbirth or whose pregnancy was terminated with abortion between February and December 2011.
main outcome measuresThe effects of endometriosis on pregnancy outcome.
resultsOf the 9,186 pregnant women in the JECS, 4,119 (44.8%) had obstetrical complications; 330 participants reported a diagnosis of endometriosis before pregnancy, and these women were at higher risk for complications of pregnancy than those without a history of endometriosis (odds ratio (OR) = 1.50; 95% confidence interval (CI) 1.20 to 1.87). Logistic regression analyses showed that the adjusted OR for obstetrical complications of pregnant women who conceived naturally and had a history of endometriosis was 1.45 (CI 1.11 to 1.90). Among pregnant women with endometriosis, the ORs of preterm premature rupture of the membranes (PROM) and placenta previa were significantly higher compared with women never diagnosed with endometriosis who conceived naturally or conceived after infertility treatment, except for ART therapy (OR 2.14, CI 1.03-4.45 and OR 3.37, CI 1.32-8.65).
conclusionsThis study showed that endometriosis significantly increased the incidence of preterm PROM and placenta previa after adjusting for confounding of the data by ART therapy.
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