ArticleACS nano2017
Cross-Linked Polymer-Stabilized Nanocomposites for the Treatment of Bacterial Biofilms.
Article in ACS nano, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 85 citations in OpenAlex.
- Using a bacterial protein to selectively target bacterial biofilms: Treatment of S. epidermidis biofilms with targeted Photothermal gold nanoparticles.Journal of colloid and interface science · 2026Article
- Eco-friendly synthesis of an antimicrobial polymer (1,4-bis(methacryloyl)piperazine) via maghnite catalysis:Frontiers in chemistry · 2026Article
- Advanced biopolymer nanocomposites for real-time biosurveillance and defense against antimicrobial resistance and viral threats.RSC advances · 2025Review
- Etrog Citron (Pharmaceutics · 2025Review
- Therapeutic Strategies to Combat Increasing Rates of Multidrug Resistant Pathogens.Pharmaceutical research · 2024Review
- Functional insights to the development of bioactive material for combating bacterial infections.Frontiers in bioengineering and biotechnology · 2023Review
- Microbial resistance to nanotechnologies: An important but understudied consideration using antimicrobial nanotechnologies in orthopaedic implants.Bioactive materials · 2022Review
- Strategies for dispersion of cariogenic biofilms: applications and mechanisms.Frontiers in microbiology · 2022Review
- Nanotechnology for Targeted Detection and Removal of Bacteria: Opportunities and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Biodegradable Poly(lactic acid) Stabilized Nanoemulsions for the Treatment of Multidrug-Resistant Bacterial Biofilms.ACS applied materials & interfaces · 2021Article
- Activity of Biodegradable Polymeric Nanosponges against Dual-Species Bacterial Biofilms.ACS biomaterials science & engineering · 2021Article
- Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections.Nature reviews. Microbiology · 2021Review
- Nanomaterials for Treating Bacterial Biofilms on Implantable Medical Devices.Nanomaterials (Basel, Switzerland) · 2020Review
- Crosslinked polymer nanocapsules for therapeutic, diagnostic, and theranostic applications.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2020Review
- High-content and high-throughput identification of macrophage polarization phenotypes.Chemical science · 2020Article
- Overcoming Multidrug-Resistant MRSA Using Conventional Aminoglycoside Antibiotics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Promising Therapeutic Strategies Against Microbial Biofilm Challenges.Frontiers in cellular and infection microbiology · 2020Review
- Rapid Identification of Biofilms Using a Robust Multichannel Polymer Sensor Array.ACS applied materials & interfaces · 2019Article
- Glycol-functionalized ionic liquids for high-temperature enzymatic ring-opening polymerization.RSC advances · 2018Article
- Dynamically crosslinked polymer nanocomposites to treat multidrug-resistant bacterial biofilms.Nanoscale · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 3 countries.
Funding
Abstract
Infections caused by bacterial biofilms are an emerging threat to human health. Conventional antibiotic therapies are ineffective against biofilms due to poor penetration of the extracellular polymeric substance secreted by colonized bacteria coupled with the rapidly growing number of antibiotic-resistant strains. Essential oils are promising natural antimicrobial agents; however, poor solubility in biological conditions limits their applications against bacteria in both dispersed (planktonic) and biofilm settings. We report here an oil-in-water cross-linked polymeric nanocomposite (∼250 nm) incorporating carvacrol oil that penetrates and eradicates multidrug-resistant (MDR) biofilms. The therapeutic potential of these materials against challenging wound biofilm infections was demonstrated through specific killing of bacteria in a mammalian cell-biofilm coculture wound model.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.