ArticleInternal and emergency medicine2017
Does early onset cataract increase the risk of ischemic stroke? A nationwide retrospective cohort study.
Article in Internal and emergency medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 2 citations in OpenAlex.
- Association between cataract and ischemic stroke risk in middle-aged adults: a retrospective cohort study in Taiwan.Irish journal of medical science · 2026Article
- Association between cataract and ischemic stroke risk in middle-aged adults: a retrospective cohort study in Taiwan.Irish journal of medical science · 2026Article
- Comorbidities in Age-Related Cataract: Epidemiological Burden and Public Health Implications.Vision (Basel, Switzerland) · 2026Review
- Association of cataract surgery with stroke among older adults in the United States.Eye (London, England) · 2025Article
- Risk Factor Analysis of Early-Onset Cataracts in Taiwan.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was attempted to address the association between early onset cataract (EOC) and ischemic stroke. Using the Longitudinal Health Insurance Database 2000, we established an EOC cohort and a comparison cohort by using 4-fold propensity score matching according to age, gender and comorbidities to detect the incidence of ischemic stroke. A Cox model was used to express the risk of ischemic stroke for the EOC patients compared with the comparison cohort. After adjusting for age, gender and comorbidities of hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, asthma, chronic obstructive pulmonary disease, chronic kidney disease, heart failure, obesity, and atrial fibrillation, the EOC patients had a 1.48-fold higher risk of ischemic stroke than the comparison cohort, but it was not statistically significant. A non-significant increase in the risk of subsequent ischemic stroke development for the EOC patients is demonstrated in this study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.