Evidence map›Paper›PMID 28004639›Full record

ArticleJournal of breath research2016

Human breath metabolomics using an optimized non-invasive exhaled breath condensate sampler.

Konstantin O Zamuruyev, Alexander A Aksenov, Alberto Pasamontes, Joshua F Brown, Dayna R Pettit, Soraya Foutouhi, Bart C Weimer, Michael Schivo, Nicholas J Kenyon, Jean-Pierre Delplanque and 1 more

Abstract read
In one paragraph

Article in Journal of breath research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Article
  3. Harnessing breath biomarkers for pneumonia diagnosis and prognosis.Expert review of respiratory medicine · 2026
    Review
  4. Review
  5. Article
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  7. Article
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  9. Article
  10. Article
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  16. Article
  17. Article
  18. Article
  19. Analytical methodologies for broad metabolite coverage of exhaled breath condensate.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Konstantin O ZamuruyevDepartment of Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Alexander A AksenovDepartment of Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Alberto PasamontesDepartment of Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Joshua F BrownDepartment of Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Dayna R PettitDepartment of Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Soraya FoutouhiSchool of Veterinary Medicine, University of California, Davis, 1089 Veterinary Medicine Drive, Davis, CA 95616, USA.
Bart C WeimerSchool of Veterinary Medicine, University of California, Davis, 1089 Veterinary Medicine Drive, Davis, CA 95616, USA.
Michael SchivoDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of California, Davis, Sacramento, CA 95617, USA.
Nicholas J KenyonDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of California, Davis, Sacramento, CA 95617, USA.
Jean-Pierre DelplanqueDepartment of Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Cristina E DavisDepartment of Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1987 to 2021
$50.1M
UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Irva Hertz-Picciotto · 2015 to 2026
$26.0M
UC Davis Clinical and Translational Science CenterUL1TR000002 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2012 to 2015
$12.2M
TRAINING IN COMPARATIVE LUNG BIOLOGY AND MEDICINET32HL007013 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI Elena Goncharova, Nicholas J. KENYON · 1985 to 2026
$10.1M
A wearable monitor for pediatric asthma: Developing environmental and breath sensors linked to spirometryU01EB022003 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DAVIS, CRISTINA ELIZABETH, KENYON, NICHOLAS J. · 2015 to 2015
$1.5M
Using Breath Metabolites to Determine Specific Virus Infection in Asthmatic PatientsK23HL127185 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SCHIVO, MICHAEL · 2016 to 2018
$526k
NCATS NIH HHS UL1 TR000002NHLBI NIH HHS K23 HL127185NHLBI NIH HHS T32 HL007013NIBIB NIH HHS U01 EB022003NIEHS NIH HHS P30 ES023513NIEHS NIH HHS P42 ES004699
6 · The paper itself

Abstract

Exhaled breath condensate (EBC) analysis is a developing field with tremendous promise to advance personalized, non-invasive health diagnostics as new analytical instrumentation platforms and detection methods are developed. Multiple commercially-available and researcher-built experimental samplers are reported in the literature. However, there is very limited information available to determine an effective breath sampling approach, especially regarding the dependence of breath sample metabolomic content on the collection device design and sampling methodology. This lack of an optimal standard procedure results in a range of reported results that are sometimes contradictory. Here, we present a design of a portable human EBC sampler optimized for collection and preservation of the rich metabolomic content of breath. The performance of the engineered device is compared to two commercially available breath collection devices: the RTube

Indexed as

ExhalationAdultBreath TestsEquipment DesignFemaleHumansMaleMetabolomeMetabolomicsSalivaSpecimen HandlingTemperatureYoung Adult

Identifiers

PMID28004639
PMCPMC5447364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.