ArticleJournal of racial and ethnic health disparities2017
Risk of Recurrence and Mortality in a Multi-Ethnic Breast Cancer Population.
Article in Journal of racial and ethnic health disparities, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Metastatic recurrence in women diagnosed with non-metastatic breast cancer: a systematic review and meta-analysis.Breast cancer research : BCR · 2024Pooled it
- Racial Differences in Breast Cancer Survival Between Black and White Women According to Tumor Subtype: A Systematic Review and Meta-Analysis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Pooled it
- Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in the Randomized TAILORx Trial.Journal of the National Cancer Institute · 2021Trial
- Outcomes of Hormone-Receptor Positive, HER2-Negative Breast Cancers by Race and Tumor Biological Features.JNCI cancer spectrum · 2021Trial
- The Assessment of Race, the 21-Gene Recurrence Score, and Breast Cancer Outcomes at Kaiser Permanente.Cancers · 2026Article
- A Real-World Evaluation of Racial Disparities in the Receipt of Cancer Treatments and Anthracycline-Based Chemotherapies in Early-Stage Breast Cancer Patients.Journal of racial and ethnic health disparities · 2026Article
- Racial disparity in pro-metastatic tumor microenvironment in treatment naïve breast cancer.NPJ breast cancer · 2026Article
- Racial disparity in tumor microenvironment and distant recurrence in residual breast cancer after neoadjuvant chemotherapy.NPJ breast cancer · 2023Article
- Article
- Racial differences in breast cancer outcomes by hepatocyte growth factor pathway expression.Breast cancer research and treatment · 2022Article
- Socioeconomic position and prognosis in premenopausal breast cancer: a population-based cohort study in Denmark.BMC medicine · 2021Article
- Obesity is an initiator of colon adenomas but not a promoter of colorectal cancer in the Black Women's Health Study.Cancer causes & control : CCC · 2020Article
- The Contribution of Race to Breast Tumor Microenvironment Composition and Disease Progression.Frontiers in oncology · 2020Review
- Racial Disparity Among Women Diagnosed With Invasive Breast Cancer in a Large Integrated Health System.Journal of patient-centered research and reviews · 2018Article
- Circulating Cell-free DNA in Serum as a Marker for the Early Detection of Tumor Recurrence in Breast Cancer Patients.Cancer diagnosis & prognosisArticle
- Does Age Matter? Estimating Risks of Locoregional Recurrence After Breast-conservative Surgery.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCompared to non-Hispanic whites, African-American women tend to be diagnosed with breast cancer at an earlier age, to have less favorable tumor characteristics, and to have poorer outcomes from breast cancer. The extent to which differences in clinical characteristics account for the black/white disparity in breast cancer mortality is unclear. The purpose of this investigation was to examine the association of clinical, demographic, and treatment variables with total mortality and breast cancer recurrence by race/ethnicity in a cohort of women diagnosed with invasive breast cancer.
methodsTo this end, we used data on 3890 invasive breast cancer cases diagnosed at a single medical center. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (95% CI) for the association of tumor characteristics and treatment variables with mortality and recurrence.
resultsCompared to white women, black women with breast cancer presented with tumors that had worse prognostic factors, particularly higher stage, lower frequency of hormone-receptor positive tumors, and higher frequency of comorbidities. Hispanics also generally had less favorable prognostic factors compared to non-Hispanic whites. Among estrogen receptor-positive cases, blacks had roughly a two-fold increased risk of recurrence compared to non-Hispanic whites. However, ethnicity/race was not associated with total mortality. Tumor stage, tumor size, and Charlson comorbidity index were positively associated with mortality, and mammography and chemotherapy and hormone therapy were inversely associated with mortality.
conclusionIn spite of poorer prognostic factors among blacks compared whites, race/ethnicity was not associated with total mortality in our study.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.