ArticleJournal of racial and ethnic health disparities2017
Research Professionals' Perspectives, Barriers, and Recommendations Regarding Minority Participation in Clinical Trials.
Article in Journal of racial and ethnic health disparities, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Representation of Hispanic Patients in Clinical Trials for Respiratory Failure: A Systematic Review.Critical care explorations · 2025Pooled it
- Progress and challenges in expanding access to clinical trials in pancreatic cancer.Communications medicine · 2026Review
- Transforming patient recruitment in clinical trials: Communication training to manage uncertainties about risks and benefits.Journal of clinical and translational science · 2026Article
- Exploring Perceptions and Motivations for Research Participation Among Black Communities.Journal of racial and ethnic health disparities · 2025Article
- Understanding Barriers and Facilitators for Ethnic Minority Groups to Audio Recording Recruitment Discussions in Clinical Trials: A Participatory Approach to Improving Informed Consent and Participation.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- "How Fluent Do I Need to Be to Say I'm Fluent?" Research Experiences of Communities that Speak Languages Other than English.Community health equity research & policy · 2025Article
- Patient participation in clinical trials conducted by principal investigators who speak one or more language(s) beyond english: Exploring ethnicity as proxy for language.Contemporary clinical trials communications · 2024Article
- Fostering diversity in clinical trials: need for evidence and implementation to improve representation.BMJ medicine · 2024Article
- DEI co-mentoring circles for clinical research professionals: A pilot project and toolkit.Journal of clinical and translational science · 2023Article
- Inclusion of Non-English-Speaking Participants in Pediatric Health Research: A Review.JAMA pediatrics · 2023Review
- Barriers and facilitators to recruitment of underrepresented research participants: Perspectives of clinical research coordinators.Journal of clinical and translational science · 2023Article
- Global Investigative Site Personnel Diversity and Its Relationship with Study Participant Diversity.Therapeutic innovation & regulatory science · 2022Article
- Perceived Institutional Barriers Among Clinical and Research Professionals: Minority Participation in Oncology Clinical Trials.JCO oncology practice · 2021Article
- Applying the Behavioural and Social Sciences Research (BSSR) Functional Framework to HIV Cure Research.Journal of the International AIDS Society · 2019Review
- Impact of Race Versus Education and Race Versus Income on Patients' Motivation to Participate in Clinical Trials.Journal of racial and ethnic health disparities · 2018Article
- Underrepresentation of Hispanics and Other Minorities in Clinical Trials: Recruiters' Perspectives.Journal of racial and ethnic health disparities · 2018Article
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims to investigate research professionals' perspectives regarding minority participation in clinical trials.
methodsA web-based survey of research professionals at US institutions receiving NIH and/or AHRQ funding to conduct clinical research in 2013. Descriptive statistics, mean, standard deviation (SD), and the Wilcoxon rank-sum test were utilized for analysis.
resultsDistributed were 13,041 surveys with 967 (7.4%) responses. Overall and race-stratified analyses included 633 and 521 surveys, respectively. A majority agreed that patients' race (mean, 3.4; SD = 1.0) and primary language (mean, 4.0; SD = 0.9) have an effect on enrollment. They had more success in enrolling those whose primary language was the same as their own (mean, 3.8; SD = 1.0), and that a language barrier and time spent arranging for interpreters had prevented them from offering a study to potential candidates (mean, 3.2; SD = 1.2). Non-Caucasian respondents were more likely to agree that "fear of unknown side effects" was a deterrent for minorities (p < 0.01), "minorities are more likely to be unavailable for follow-up phone calls" (p = 0.07), and "the unavailability of translated material discourages non-English speakers from participation" (p = 0.08). They also were more likely to be neutral or agree with being discouraged from enrolling minorities because of the possibility of their withdrawal or being less likely to be available for phone follow-ups and follow-up visits (all p < 0.01).
conclusionDespite a few subtle racial differences in research professionals' perspectives, a majority expressed no hesitation in enrolling minorities. Patients' race and primary language appeared to influence enrollment. A language barrier appeared to be the strongest barrier for research professionals.
Indexed as
Identifiers
28004355What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.