ArticleJournal of plant research2017
A subclass of HSP70s regulate development and abiotic stress responses in Arabidopsis thaliana.
Article in Journal of plant research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed, 85 citations in OpenAlex.
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- Transcriptomic Analysis of Osmotic Stress-Tolerant Somatic Embryos ofInternational journal of molecular sciences · 2025Article
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- Insights into the Heat Shock Protein 70 (Hsp70) Family inPlants (Basel, Switzerland) · 2024Article
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- Heat shock protein 70 is associated with duration of cell proliferation in early pod development of soybean.Communications biology · 2024Article
- Developing affordable and efficient heating devices for enhanced live cell imaging in confocal microscopy.Frontiers in plant science · 2024Article
- Genome-wide identification and expression analysis of heat shock protein gene family in cassava.The plant genome · 2023Article
- Genome-wide identification and expression analysis of3 Biotech · 2023Article
- Overexpression of AHL proteins enhances root hair production by altering the transcription of RHD6-downstream genes.Plant direct · 2023Article
- Temperature changes in the root ecosystem affect plant functionality.Plant communications · 2023Article
- Bradyrhizobium japonicum IRAT FA3 promotes salt tolerance through jasmonic acid priming in Arabidopsis thaliana.BMC plant biology · 2023Article
- Exploration of the truncated cytosolic Hsp70 in plants - unveiling the diverse T1 lineage and the conserved T2 lineage.Frontiers in plant science · 2023Article
- Gain-of-function of the cytokinin response activator ARR1 increases heat shock tolerance inPlant signaling & behavior · 2022Article
- Mitochondrial HSC70-1 Regulates Polar Auxin Transport through ROS Homeostasis in Arabidopsis Roots.Antioxidants (Basel, Switzerland) · 2022Article
- Ethanol treatment enhances drought stress avoidance in cassava (Manihot esculenta Crantz).Plant molecular biology · 2022Article
- HSP70 Gene Family inCells · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Members of the HSP70 family function as molecular chaperones to maintain cellular homeostasis and help plants cope with environmental stimuli. However, due to functional redundancy and lack of effective chemical inhibitors, our knowledge of functions of individual HSP70s has remained limited. Here, we confirmed a subclass of HSP70s, including HSP70-1, -2, -3, -4, and -5, localized to the cytosol and nucleus in Arabidopsis thaliana. Histochemical analyses of promoter:GUS reporter lines showed that HSP70-1, -2, -3, and -4 genes were widely expressed, but HSP70-5 was not. In addition, individual HSP70 showed not only similar but also distinct transcriptions when treated by different abiotic stresses and phytohormones. No apparent phenotype was observed when individual HSP70 genes were overexpressed or knocked-out/down, but the double mutant hsp70-1 hsp70-4 and triple mutant hsp70-2 hsp70-4 hsp70-5 plants exhibited developmental phenotypes with shortened specific growth periods, curly and round leaves, twisted petioles, thin stems, and short siliques. Moreover, both mutants were hypersensitive to heat, cold, high glucose, salt and osmotic stress, but hyposensitive to abscisic acid. Genes related to flowering, and the cytokinin, brassinosteroid, and abscisic acid signaling pathways were differentially expressed in both mutants. Our studies suggest that, the individual HSP70 possibly performs both redundant and specific functions with the other members in the cytosolic/nuclear HSP70 subclass, and apart from enabling plants to cope with abiotic stresses, this subclass of cytosolic/nuclear HSP70 proteins also participates in diverse developmental processes and signaling pathways.
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