Evidence map›Paper›PMID 28004265›Full record

ArticleWiener klinische Wochenschrift2017

Active surveillance for low-risk prostate cancer in Austria: the online registry of the Qualitätspartnerschaft Urologie (QuapU).

Klaus Eredics, Karl Dorfinger, Gero Kramer, Anton Ponholzer, Stephan Madersbacher

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Article in Wiener klinische Wochenschrift, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Klaus EredicsDepartment of Urology, Kaiser-Franz-Josef Spital, Kundratstrasse 3, 1100, Vienna, Austria.
Karl DorfingerUrological Practice, Vienna, Austria.
Gero KramerDepartment of Urology, Medical University of Vienna, Vienna, Austria.
Anton PonholzerDepartment of Urology, Krankenhaus der Barmherzigen Brüder, Vienna, Austria.
Stephan MadersbacherDepartment of Urology, Kaiser-Franz-Josef Spital, Kundratstrasse 3, 1100, Vienna, Austria. stephan.madersbacher@wienkav.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundActive surveillance (AS) is a well-recognized strategy to reduce the risk of overtreatment in men with low-risk prostate cancer. No data on this approach are available from Austria.

methodsThe Qualitätspartnerschaft Urologie (QuapU) developed an online database for patients managed with AS in Austria. Principal inclusion/exclusion criteria corresponded to those of the S3 prostate cancer guideline of German urologists: prostate-specific antigen (PSA) <10 ng/ml, Gleason score <7 (maximum 20% of biopsies being positive). Control visits were scheduled at 3‑month intervals, control biopsies were scheduled at 12 and 36 months.

resultsTo date 131 patients have been entered into this data base. Mean patient age is 64 years, 6% were younger than 50 years, two thirds of patients were aged 50-70 years and 25% were older than 70 years. Mean PSA value was 5.9 ng/ml (PSA 0-4 ng/ml: 15%; PSA >4-10 ng/ml: 85%). The prostate volume averaged 39 ml. The mean time under AS was 17.5 months (<12 months: 60%; >12 months: 40%). The AS adherence at 12 months was 85% and at 24 months 76%. To date, a total of 23 patients (17.6%) stopped AS. The most frequent reasons for discontinuing AS were patient wish for active treatment (43.5%) and PSA progression (30.4%). A histological progression was rarely seen (6.1%) and the control biopsy rate was low (19.8%).

conclusionThis study is the first description of AS in Austria and documents the feasibility of an online registry for AS. The data confirm the international experience with this approach with acceptable adherence rates.

Indexed as

RegistriesAgedAged, 80 and overAge DistributionAustriaFeasibility StudiesHumansIncidenceInternetMaleMiddle AgedOnline SystemsPopulation SurveillanceProstatic NeoplasmsRisk FactorsSex DistributionActive surveillanceBiopsyDisease progressionLocalised prostate cancerLow risk diseaseProstate cancerProstate-specific antigenProstatic neoplasmsPSA

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.