Evidence map›Paper›PMID 28004030›Full record

ReviewGynecologic oncology reports2017

Clinical trials in low and middle-income countries - Successes and challenges.

Surbhi Grover, Melody Xu, Anuja Jhingran, Umesh Mahantshetty, Linus Chuang, William Small, David Gaffney

Open access · goldAbstract readReview
In one paragraph

Review in Gynecologic oncology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Tackling the lack of diversity in cancer research.Disease models & mechanisms · 2023
    Article
  12. Disparities in COVID-19 clinical studies from high-income and low-and middle-income countries.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Article
  13. Article
  14. Review
  15. Equity in Radiation Oncology Trials: from Knowledge Generation to Clinical Translation.International journal of radiation oncology, biology, physics · 2022
    Article
  16. Are We Scared of Clinical Trials if Not Sufficiently Informed and Educated?Advances in medical education and practice · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 2 countries.

Surbhi GroverDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, United States.
Melody XuDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, United States.
Anuja JhingranDivision of Radiation Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, United States.
Umesh MahantshettyDepartment of Radiation Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.
Linus ChuangDepartment of Gynecological Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
William SmallDepartment of Radiation Oncology, Loyola University, Chicago, IL, United States.
David GaffneyDepartment of Radiation Oncology, University of Utah, Salt Lake City, UT, United States.
Icahn School of Medicine at Mount Sinai · USLoyola University Chicago · USTata Memorial Hospital · INThe University of Texas MD Anderson Cancer Center · USUniversity of California, San Francisco · USUniversity of Pennsylvania · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gynecologic malignancies affect women in low and middle-income countries (LMICs) at equal or higher rates compared to high income countries (HICs), yet practice guidelines based on clinical trials performed in HICs do not routinely account for resource disparities between these regions. There is a need and growing interest for executing clinical trials in LMICs. This has led to the creation of multinational cooperative groups and the initiation of several ongoing clinical trials in Mexico, China, and Korea. In this article we describe the challenges involved in initiating clinical trials in LMICs, review current efforts within surgical, medical, and radiation oncology, and introduce high priority topics for future research.

Indexed as

Clinical trialsGynecological cancersLow and middle-income countries

Identifiers

PMID28004030
PMCPMC5157789
OpenAlexW2554147819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.