Evidence map›Paper›PMID 28003864›Full record

ArticleOxidative medicine and cellular longevity2016

Virus Infections on Prion Diseased Mice Exacerbate Inflammatory Microglial Response.

Nara Lins, Luiz Mourão, Nonata Trévia, Aline Passos, José Augusto Farias, Jarila Assunção, Amanda Quintairos, João Bento-Torres, Marcia Consentino Kronka Sosthenes, José Antonio Picanço Diniz and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Nara LinsUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.
Luiz MourãoUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.
Nonata TréviaUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.
Aline PassosUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.
José Augusto FariasUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.
Jarila AssunçãoUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.
Amanda QuintairosUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.ORCID 0000-0002-9567-0829
João Bento-TorresUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.
Marcia Consentino Kronka SosthenesUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.
José Antonio Picanço DinizInstituto Evandro Chagas, Laboratório de Microscopia Eletrônica and Departamento de Arbovirologia e Febres Hemorrágicas Virais, Belém, Brazil.
Pedro Fernando da Costa VasconcelosInstituto Evandro Chagas, Laboratório de Microscopia Eletrônica and Departamento de Arbovirologia e Febres Hemorrágicas Virais, Belém, Brazil.
Cristovam Wanderley Picanço-DinizUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Investigações em Neurodegeneração e Infecção no Hospital Universitário João de Barros Barreto, Belém, Brazil.ORCID 0000-0001-6611-6880
Universidade Federal do Pará · BRInstituto Evandro Chagas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated possible interaction between an arbovirus infection and the ME7 induced mice prion disease. C57BL/6, females, 6-week-old, were submitted to a bilateral intrahippocampal injection of ME7 prion strain (ME7) or normal brain homogenate (NBH). After injections, animals were organized into two groups: NBH (

Indexed as

CoinfectionAnimalsAntigens, ViralArbovirusesBehavior, AnimalCA1 Region, HippocampalCalcium-Binding ProteinsDisease Models, AnimalDisease ProgressionEncephalitis, ArbovirusFemaleMice, Inbred C57BLMicrofilament ProteinsMicrogliaMotor ActivityNerve DegenerationAif1 protein, mouseAntigens, ViralCalcium-Binding ProteinsMicrofilament Proteins

Identifiers

PMID28003864
PMCPMC5149707
OpenAlexW2551297304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.