Evidence map›Paper›PMID 28003732›Full record

ArticleMolecular vision2016

Regulation of photoreceptor gene transcription via a highly conserved transcriptional regulatory element by

Yi Pan, Daniel F Comiskey, Lisa E Kelly, Dawn S Chandler, Heithem M El-Hodiri

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Molecular vision, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yi PanCenter for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH.
Daniel F ComiskeyGraduate Program in Molecular, Cellular, and Developmental Biology, The Ohio State University, Columbus, OH; Center for Childhood Cancer, The Research Institute at Nationwide Children's Hospital, Columbus, OH; Center for RNA Biology, Wexner Medical Center, The Ohio State University, Columbus, OH.
Lisa E KellyCenter for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH.
Dawn S ChandlerGraduate Program in Molecular, Cellular, and Developmental Biology, The Ohio State University, Columbus, OH; Center for Childhood Cancer, The Research Institute at Nationwide Children's Hospital, Columbus, OH; Center for RNA Biology, Wexner Medical Center, The Ohio State University, Columbus, OH; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH.
Heithem M El-HodiriCenter for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH; Graduate Program in Molecular, Cellular, and Developmental Biology, The Ohio State University, Columbus, OH; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH.
Nationwide Children's Hospital · US

Funding

The Role of Rx in Retinal Progenitor Cell DevelopmentR01EY015480 · NEI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI EL-HODIRI, HEITHEM M · 2004 to 2015
$3.7M
NEI NIH HHS R01 EY015480
6 · The paper itself

Abstract

purposeThe photoreceptor conserved element-1 (PCE-1) sequence is found in the transcriptional regulatory regions of many genes expressed in photoreceptors. The

methods

resultsWe identified one

conclusions

Indexed as

AnimalsElectrophoretic Mobility Shift AssayEye ProteinsGene AmplificationGene Expression Regulation, DevelopmentalGenes, HomeoboxHomeodomain ProteinsIn Situ HybridizationPhotoreceptor CellsPolymerase Chain ReactionPromoter Regions, GeneticRegulatory Elements, TranscriptionalRNA, MessengerSequence Homology, Amino AcidTranscription FactorsTranscription, GeneticEye ProteinsHomeodomain ProteinsRNA, MessengerTranscription FactorsXenopus Proteins

Identifiers

PMID28003732
PMCPMC5166794
OpenAlexW2565201457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.