Evidence map›Paper›PMID 28003656›Full record

ReviewNature reviews. Neuroscience2017

Closed-loop brain training: the science of neurofeedback.

Ranganatha Sitaram, Tomas Ros, Luke Stoeckel, Sven Haller, Frank Scharnowski, Jarrod Lewis-Peacock, Nikolaus Weiskopf, Maria Laura Blefari, Mohit Rana, Ethan Oblak and 2 more

Erratum issued 11 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 11 registered trials, which are not on this map. Cited by 514 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
514citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03805854 nacompletednot on this mapstarted 2019, after this paper: background citation

Modulating Pain Using Transcranial Alternating Stimulation (tACS) in Healthy Human Subjects

TypeinterventionalSponsorTechnical University of MunichRan2019 to 2019Enrolled39ConditionsExperimental Pain in Healthy Human SubjectsArms10 Hz tACS of the bilateral somatosensory cortex, 10 Hz tACS of the prefrontal cortex, 80 Hz tACS of the bilateral somatosensory cortex, 80 Hz tACS of the prefrontal cortex, Sham stimulation of the bilateral somatosensory cortex
NCT03994042 nacompletednot on this mapstarted 2019, after this paper: background citation

EEG-based Mental Imagery Feedback in Stroke Patients With Severe Hand Dysfunction

TypeinterventionalSponsorMälardalen UniversityRan2019 to 2020Enrolled2ConditionsStroke, HemiparesisArmsMental imagery neurofeedback training
NCT05112042 completednot on this mapstarted 2022, after this paper: background citation

Detection and Classification of Levels of Consciousness Using Parietal EEG-fNIRS During Anesthesia

TypeobservationalSponsorPontificia Universidad Catolica de ChileRan2022 to 2023Enrolled13ConditionsAnesthesia, Consciousness, Loss of
NCT05456958 narecruitingnot on this mapstarted 2023, after this paper: background citation

Self-regulation of Post-traumatic Stress Disorder (PTSD) Neurocircuitry Using Multiple Sessions of Real-Time Functional Magnetic Resonance Imaging (RtfMRI)

TypeinterventionalSponsorAndrew NicholsonRan2023 to 2025Enrolled60ConditionsPost Traumatic Stress DisorderArmsMRI Biofeedback, Sham-MRI Biofeedback
NCT05570695 nacompletednot on this mapstarted 2022, after this paper: background citation

How do Alpha Oscillations Shape the Perception of Pain? - An EEG-based Neurofeedback Study

TypeinterventionalSponsorTechnical University of MunichRan2022 to 2023Enrolled75ConditionsExperimental Pain in Healthy Human SubjectsArmsattention right training, ARTNF, attention left training, ALTNF, sham attention right training, ARTsham, sham attention left training, ALTsham
NCT05627895 completednot on this mapstarted 2023, after this paper: background citation

A Feasibility Study of fMRI-neurofeedback in Parkinson's Disease

TypeobservationalSponsorMaastricht UniversityRan2023 to 2024Enrolled12ConditionsBasal-ganglia fMRI NeurofeedbackArmsNeurofeedback
NCT05778448 nacompletednot on this mapstarted 2021, after this paper: background citation

Brain-computer Interface (BCI) Based Closed-loop Training for Hemiparetic Upper Extremities in Patients Due to Stroke: A Randomized Controlled Study

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2021 to 2023Enrolled30ConditionsStroke, Brain Computer InterfaceArmsBrain Computer Interface/ Functional Electrical Stimulation/ Virtual Reality
NCT05936697 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Neurofeedback Training to Improve Prefrontal Functioning in Older Adults With Subclinical Depression and Anxiety: a Randomised Control Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2023 to 2024Enrolled90ConditionsDepression, AnxietyArmsfNIRS, EEG, Baseline Training
NCT06460207 naunknown statusnot on this mapstarted 2024, after this paper: background citation

A 4-day Study of Neurofeedback Training of Cognitive Control in Healthy Adults

TypeinterventionalSponsorUniversity of Texas at AustinRan2024 to 2025Enrolled40ConditionsNeurofeedback, Cognitive Training, Memory, Short-Term, Functional Magnetic Resonance Imaging (fMRI)ArmsfMRI neurofeedback
NCT06582355 narecruitingnot on this mapstarted 2025, after this paper: background citation

MOTOR-NF - a Randomized Controlled Trial of FMRI-based Neurofeedback for Motor Symptoms of Parkinson's Disease

TypeinterventionalSponsorMaastricht University Medical CenterRan2025 to 2026Enrolled60ConditionsParkinson DiseaseArmsNeurofeedback, Kinesthetic imagery
NCT06779825 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Impact of Stimulants and In-Scanner Motion on FMRI Neurofeedback and Task Performance in ADHD

TypeobservationalSponsorBoston Children's HospitalRan2025 to 2026Enrolled30ConditionsADHDArmsfMRI Neurofeedback attention task
3 · Its place in the literature

Who cites it

514 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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454 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Ranganatha SitaramInstitute for Biological and Medical Engineering, Department of Psychiatry, and Section of Neuroscience, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860 Hernán Briones, piso 2, Macul 782-0436, Santiago, Chile.
Tomas RosNeurology and Imaging of Cognition Lab, University of Geneva, 1 rue Michel-Servet, 1211 Geneva, Switzerland.
Luke StoeckelNational Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, 6707 Democracy Boulevard, Bethesda, Maryland 20892, USA.
Sven HallerAffidea Centre Diagnostique Radiologique de Carouge CDRC, Clos de la Fonderie 1, 1277 Carouge, Switzerland.
Frank ScharnowskiPsychiatric University Hospital, University of Zürich, Lenggstrasse 31, 8032 Zürich, Switzerland.
Jarrod Lewis-PeacockDepartment of Psychology, Imaging Research Center, University of Texas at Austin, 108 E Dean Keeton Street, Austin, Texas 78712, USA.
Nikolaus WeiskopfDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1, 04103 Leipzig, Germany.
Maria Laura BlefariDefitech Chair in Brain-Machine Interface, Center for Neuroprosthetics, École Polytechnique Fédérale de Lausanne, Chemin de Mines 9, 1202 Geneva, Switzerland.
Mohit RanaInstitute for Biological and Medical Engineering, Department of Psychiatry, and Section of Neuroscience, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860 Hernán Briones, piso 2, Macul 782-0436, Santiago, Chile.
Ethan OblakDepartment of Mechanical Engineering, University of Texas at Austin, 204 E Dean Keeton Street, Austin, Texas 78712, USA.
Niels BirbaumerWyss Center for Bio and Neuroengeneering, Chenin de Mines 9, 1202 Geneva, Switzerland.
James SulzerDepartment of Mechanical Engineering, University of Texas at Austin, 204 E Dean Keeton Street, Austin, Texas 78712, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurofeedback is a psychophysiological procedure in which online feedback of neural activation is provided to the participant for the purpose of self-regulation. Learning control over specific neural substrates has been shown to change specific behaviours. As a progenitor of brain-machine interfaces, neurofeedback has provided a novel way to investigate brain function and neuroplasticity. In this Review, we examine the mechanisms underlying neurofeedback, which have started to be uncovered. We also discuss how neurofeedback is being used in novel experimental and clinical paradigms from a multidisciplinary perspective, encompassing neuroscientific, neuroengineering and learning-science viewpoints.

Indexed as

AnimalsAttention Deficit Disorder with HyperactivityBrainHumansLearningNeurofeedbackNeuroimagingNeuronal PlasticitySelf-ControlStroke Rehabilitation

Identifiers

PMID28003656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 5 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.