ArticleProceedings of the National Academy of Sciences of the United States of America2017
Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3.
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In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
What it found
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Targeted Therapies for Skeletal Muscle Ion Channelopathies: Systematic Review and Steps Towards Precision Medicine.Journal of neuromuscular diseases · 2021Pooled it
- Genomic Insights into the Origins, Population Structure, and Local Adaptation of Philippine Visayan Native Cattle.Animals : an open access journal from MDPI · 2026Article
- STAC3 binding to CaV1.1 II-III loop is nonessential but critically supports skeletal muscle excitation-contraction coupling.JCI insight · 2025Article
- Two zebrafish cacna1s loss-of-function variants provide models of mild and severe CACNA1S-related myopathy.Human molecular genetics · 2024Article
- CaHandbook of experimental pharmacology · 2023Article
- The implementation and utility of clinical exome sequencing in a South African infant cohort.Frontiers in genetics · 2023Article
- Postdevelopmental knockout of Orai1 improves muscle pathology in a mouse model of Duchenne muscular dystrophy.The Journal of general physiology · 2022Article
- Superfast excitation-contraction coupling in adult zebrafish skeletal muscle fibers.The Journal of general physiology · 2022Article
- Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.Nature communications · 2021Article
- Stac protein regulates release of neuropeptides.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- A "crush" course on rhabdomyolysis: risk stratification and clinical management update for the perioperative clinician.Journal of anesthesia · 2020Review
- Zebrafish models of sarcopenia.Disease models & mechanisms · 2020Review
- Excitation-contraction coupling in skeletal muscle: recent progress and unanswered questions.Biophysical reviews · 2020Review
- Dstac Regulates Excitation-Contraction Coupling inFrontiers in physiology · 2020Article
- The binding interactions that maintain excitation-contraction coupling junctions in skeletal muscle.The Journal of general physiology · 2019Article
- STAC3 incorporation into skeletal muscle triads occurs independent of the dihydropyridine receptor.Journal of cellular physiology · 2018Article
- Stac Proteins Suppress CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Allosteric regulators selectively prevent CaeLife · 2018Article
- Duplex signaling by CaM and Stac3 enhances CaThe Journal of general physiology · 2018Article
- Dstac is required for normal circadian activity rhythms in Drosophila.Chronobiology international · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Jeremy W LinsleyCell and Molecular Biology Program, University of Michigan, Ann Arbor, MI 48109.
I-Uen HsuDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Linda GroomDepartment of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642.
Viktor YarotskyyDepartment of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642.
Manuela LavoratoDepartment of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104.
Eric J HorstickDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Drew LinsleyDepartment of Cognitive, Linguistic, and Psychological Sciences, Brown University, Providence, RI 02912.
Wenjia WangDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Clara Franzini-ArmstrongDepartment of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104; armstroc@mail.med.upenn.edu robert_dirksen@urmc.rochester.edu kuwada@umich.edu.
Robert T DirksenDepartment of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642; armstroc@mail.med.upenn.edu robert_dirksen@urmc.rochester.edu kuwada@umich.edu.
John Y KuwadaCell and Molecular Biology Program, University of Michigan, Ann Arbor, MI 48109; armstroc@mail.med.upenn.edu robert_dirksen@urmc.rochester.edu kuwada@umich.edu.
University of Michigan–Ann Arbor · USUniversity of Rochester Medical Center · USUniversity of Pennsylvania · USBrown University · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US
Funding
Uncovering the Molecular Basis of Malignant HyperthermiaP01AR052354 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PESSAH, ISSAC N · 2006 to 2016
$13.4MCELLULAR AND MOLECULAR BIOLOGY AT MICHIGANT32GM007315 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PUTHENVEEDU, MANOJKUMAR A · 1985 to 2021
$12.8MBasis of Muscle Dysfunction in Malignant Hyperthermia & Central Core DiseaseR01AR053349 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI DIRKSEN, ROBERT T, HAMILTON, SUSAN L · 2006 to 2020
$8.0MMolecular Mechanism and Functional Role of SOCE in Skeletal MuscleR01AR059646 · NIAMS · UNIVERSITY OF ROCHESTER · PI DIRKSEN, ROBERT T · 2010 to 2020
$3.6MAnalysis of a Novel Regulator of Excitation-Contraction Coupling in Skeletal MuscR01AR063056 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KUWADA, JOHN Y · 2013 to 2017
$1.8MNuclear ryanodine receptor type 1: Role in skeletal muscle physiology and diseaseK01AR060831 · NIAMS · UNIVERSITY OF ROCHESTER · PI YAROTSKYY, VIKTOR · 2011 to 2015
$483kNIAMS NIH HHS K01 AR060831NIAMS NIH HHS P01 AR052354NIAMS NIH HHS R01 AR053349NIAMS NIH HHS R01 AR059646NIAMS NIH HHS R01 AR063056NIGMS NIH HHS T32 GM007315
Abstract
Skeletal muscle contractions are initiated by an increase in Ca
Indexed as
Adaptor Proteins, Signal TransducingAnimalsAnimals, Genetically ModifiedCaffeineCalciumCalcium Channels, L-TypeEmbryo, NonmammalianMicroscopy, ElectronMuscle Fibers, SkeletalMutationMyotonia CongenitaRyanodine Receptor Calcium Release ChannelZebrafishZebrafish ProteinsAdaptor Proteins, Signal TransducingCaffeineCalciumCalcium Channels, L-TypeRyanodine Receptor Calcium Release ChannelStac3 protein, zebrafishZebrafish Proteinsdihydropyridine receptorexcitation–contraction couplingNative American myopathyskeletal musclezebrafish
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.