Evidence map›Paper›PMID 28003406›Full record

ReviewJournal of neurophysiology2017

Interfacing to the brain's motor decisions.

Giovanni Mirabella, Mikhail А Lebedev

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03665493 (Dopamine Effect on Inhibitory Control), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03665493 nacompletednot on this mapstarted 2020, after this paper: background citation

Dopamine Effect on Inhibitory Control

TypeinterventionalSponsorGiovanni MirabellaRan2020 to 2023Enrolled90ConditionsIdiopathic Parkinson's DiseaseArmsPD patients H&Y=1.5-2 Medications ON, PD patients H&Y=1.5-2 Medications OFF, Healthy age-matched controls, PD patients H&Y=3 Medications OFF, PD patients H&Y=3 Medications ON
3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. A brief review of motor imagery and bimanual coordination.Frontiers in human neuroscience · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Commentary: Injecting Instructions into Premotor Cortex.Frontiers in cellular neuroscience · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giovanni MirabellaIstituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy.ORCID 0000-0002-4405-2609
Mikhail А LebedevDuke University Center for Neuroengineering, Durham, North Carolina lebedev@neuro.duke.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been long known that neural activity, recorded with electrophysiological methods, contains rich information about a subject's motor intentions, sensory experiences, allocation of attention, action planning, and even abstract thoughts. All these functions have been the subject of neurophysiological investigations, with the goal of understanding how neuronal activity represents behavioral parameters, sensory inputs, and cognitive functions. The field of brain-machine interfaces (BMIs) strives for a somewhat different goal: it endeavors to extract information from neural modulations to create a communication link between the brain and external devices. Although many remarkable successes have been already achieved in the BMI field, questions remain regarding the possibility of decoding high-order neural representations, such as decision making. Could BMIs be employed to decode the neural representations of decisions underlying goal-directed actions? In this review we lay out a framework that describes the computations underlying goal-directed actions as a multistep process performed by multiple cortical and subcortical areas. We then discuss how BMIs could connect to different decision-making steps and decode the neural processing ongoing before movements are initiated. Such decision-making BMIs could operate as a system with prediction that offers many advantages, such as shorter reaction time, better error processing, and improved unsupervised learning. To present the current state of the art, we review several recent BMIs incorporating decision-making components.

Indexed as

Brain-Computer InterfacesAnimalsBrainDecision MakingFeedback, SensoryHumansMotor Activityaction valuebehavioral flexibilitybrain-computer interfacebrain-machine interfacedecision makingrewardvoluntary motor control

Identifiers

PMID28003406
PMCPMC5350270

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.