Evidence map›Paper›PMID 28003300›Full record

ArticleBMJ open2016

Protocol for developing, disseminating and implementing a core outcome set for endometriosis.

Martin Hirsch, James M N Duffy, Claire Barker, Lone Hummelshoj, Neil P Johnson, Ben Mol, Khalid S Khan, Cindy Farquhar, International Collaboration to Harmonize Outcomes and Measures for Endometriosis (iHOME)

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Consensus on Symptom Selection for Endometriosis Questionnaires: A Modified e-Delphi Study.BJOG : an international journal of obstetrics and gynaecology · 2025
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  8. Development of a core outcome domain set for clinical research on capillary malformations (the COSCAM project).Journal of the European Academy of Dermatology and Venereology : JEADV · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Martin HirschWomen's Health Research Unit, Barts and the London School of Medicine and Dentistry, London, UK.
James M N DuffyBalliol College, University of Oxford, Oxford, UK.
Claire BarkerRadcliffe Women's Health Patient Participation Group, University of Oxford, Oxford, UK.
Lone HummelshojWorld Endometriosis Society, Vancouver, British Columbia, Canada.
Neil P JohnsonWorld Endometriosis Society, Vancouver, British Columbia, Canada.
Ben MolRobinson Research Institute, University of Adelaide, Adelaide, South Australia, Australia.
Khalid S KhanWomen's Health Research Unit, Barts and the London School of Medicine and Dentistry, London, UK.
Cindy FarquharCochrane Gynaecology and Fertility Group, University of Auckland, Auckland, New Zealand.
International Collaboration to Harmonize Outcomes and Measures for Endometriosis (iHOME)
University of Adelaide · AUUniversity of Oxford · GBEndometriosis · GBUniversity of Auckland · NZ

Funding

Department of Health DRF-2014-07-051
6 · The paper itself

Abstract

introductionEndometriosis is a common gynaecological disease characterised by pain and subfertility. Randomised controlled trials evaluating treatments for endometriosis have reported many different outcomes and outcome measures. This variation restricts effective data synthesis limiting the usefulness of research to inform clinical practice. To address these methodological concerns, we aim to develop, disseminate and implement a core outcome set for endometriosis engaging with key stakeholders, including healthcare professionals, researchers and women with endometriosis. METHODS AND ANALYSIS: An international steering group has been established, including healthcare professionals, researchers and patient representatives. Potential outcomes identified from a systematic review of the literature will be entered into a modified Delphi method. Key stakeholders will be invited to participate including healthcare professionals, researchers and women with endometriosis. Participants will be invited to score individual outcomes on a nine-point Likert scale anchored between 1 (not important) and 9 (critical). Repeated reflection and rescoring should promote whole and individual stakeholder group converge towards consensus, 'core', outcomes. High-quality outcome measures will be associated with core outcomes. ETHICS AND DISSEMINATION: The implementation of a core outcome set for endometriosis within future clinical trials, systematic reviews and clinical guidelines will enhance the availability of comparable data to facilitate evidence-based patient care. This study was prospectively registered with Core Outcome Measures in Effectiveness Trials Initiative; number: 691.

Indexed as

ConsensusOutcome Assessment, Health CareResearch DesignDelphi TechniqueEndometriosisFemaleHealth PersonnelHumansPatientsResearch PersonnelStakeholder ParticipationTranslational Research, BiomedicalConsensus methodologyCore outcome setsEndometriosisoutcome harmonizationOutcome variation

Identifiers

PMID28003300
PMCPMC5223702
OpenAlexW2566188804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.