ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2017
Impulsivity Moderates Subjective Responses to Alcohol in Alcohol-Dependent Individuals.
Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Differential effects of UPPS-P impulsivity on subjective alcohol response and craving: An experimental test of acquired preparedness.Experimental and clinical psychopharmacology · 2023Trial
- Relationships between generalized impulsivity and subjective stimulant and sedative responses following alcohol administration.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019Trial
- Event-level impacts of proximal responsibilities and impulsive traits on drinking behavior during real-world drinking episodes.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- A pilot study of impulsivity and subjective alcohol response in the lab and moment.Experimental and clinical psychopharmacology · 2025Article
- Subjective intoxication predicts alcohol-related consequences at equivalent alcohol concentrations in young adults using ecological momentary assessment and alcohol sensors.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024Article
- Psychological dimensions in alcohol use disorder: comparing active drinkers and abstinent patients.Frontiers in psychiatry · 2024Article
- A new paradigm for addictions.Alcohol and alcoholism (Oxford, Oxfordshire) · 2023Article
- Moderators of subjective response to alcohol in the human laboratory.Alcoholism, clinical and experimental research · 2022Article
- Rewarding Subjective Effects of the NMDAR Antagonist Nitrous Oxide (Laughing Gas) Are Moderated by Impulsivity and Depressive Symptoms in Healthy Volunteers.The international journal of neuropsychopharmacology · 2021Article
- Subjective response to alcohol: Associated alcohol use and orbitofrontal gray matter volume in bipolar disorder.Journal of affective disorders · 2021Article
- Ethanol induces maladaptive impulse control and decreased seeking behaviors in mice.Addiction biology · 2020Article
- To Infuse or Ingest in Human Laboratory Alcohol Research.Alcoholism, clinical and experimental research · 2020Review
- Does Self-Reported or Behavioral Impulsivity Predict Subjective Response to Low-Dose Alcohol?Alcohol and alcoholism (Oxford, Oxfordshire) · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsStudies of social drinkers indicate that subjective response (SR) to alcohol and impulsivity are risk factors for the development of alcohol use disorder which may be related. It is unclear, however, whether there are significant relationships between SR and impulsivity among individuals with alcohol dependence. Using data from an intravenous (IV) alcohol challenge study, the present study is the first to explore the relationship between impulsivity and SR during alcohol administration among alcohol-dependent individuals.
methodsNon-treatment-seeking, alcohol-dependent individuals (N = 42) completed the Delay Discounting Task to measure impulsivity and then completed two counterbalanced, placebo-controlled IV alcohol administration sessions, which included assessments of SR at breath alcohol concentration (BrAC) levels of 0.00, 0.02, 0.04 and 0.06 g/dl.
resultsAnalyses revealed that more impulsive participants experienced higher subjective stimulation and positive mood in response to rising BrACs as compared to less impulsive individuals. More impulsive participants also experienced increased sedation over time regardless of condition (i.e. alcohol vs. saline).
conclusionThese findings suggest that among alcohol-dependent individuals, impulsivity is positively associated with the hedonic effects of alcohol as compared to placebo. High impulsivity may characterize a subset of alcohol-dependent individuals who drink to experience the rewarding effects of alcohol.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.