Evidence map›Paper›PMID 28003193›Full record

ArticleApplied and environmental microbiology2017

Fermentative Production of Cysteine by Pantoea ananatis.

Kazuhiro Takumi, Mikhail Kharisovich Ziyatdinov, Viktor Samsonov, Gen Nonaka

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
8.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Microbial Production Potential ofMicroorganisms · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Kazuhiro TakumiResearch Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc., Kawasaki, Japan.
Mikhail Kharisovich ZiyatdinovAjinomoto-Genetika Research Institute, Moscow, Russia.
Viktor SamsonovAjinomoto-Genetika Research Institute, Moscow, Russia.
Gen NonakaResearch Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc., Kawasaki, Japan gen_nonaka@ajinomoto.com.
Ajinomoto (Japan) · JPAjinomoto (Russia) · RUGenetika · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cysteine is a commercially important amino acid; however, it lacks an efficient fermentative production method. Due to its cytotoxicity, intracellular cysteine levels are stringently controlled via several regulatory modes. Managing its toxic effects as well as understanding and deregulating the complexities of regulation are crucial for establishing the fermentative production of cysteine. The regulatory modes include feedback inhibition of key metabolic enzymes, degradation, efflux pumps, and the transcriptional regulation of biosynthetic genes by a master cysteine regulator, CysB. These processes have been extensively studied using

Indexed as

FermentationAmino AcidsBacterial ProteinsBiotechnologyCystathionine gamma-LyaseCysteineDown-RegulationDrug Resistance, BacterialEscherichia coliGene Expression Regulation, BacterialGenetic EngineeringMetabolic Networks and PathwaysPantoeaSequence DeletionAmino AcidsBacterial ProteinsCcdA protein, BacteriaCysB protein, BacteriaCystathionine gamma-LyaseCysteineamino acid fermentationcysteinecysteine desulfhydrasecysteine effluxPantoea ananatis

Identifiers

PMID28003193
PMCPMC5311407
OpenAlexW2561831109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.